Department of Anesthesiology and Operating Room, Traditional and Complementary Medicine Research Center, Addiction Institute, Mazandaran University of Medical Sciences, Sari, Iran.
Department of History of Medical Sciences, School of Allied of Medical Sciences, Mazanadaran University of Medical Sciences, Sari, Iran.
Arch Toxicol. 2023 Apr;97(4):981-989. doi: 10.1007/s00204-023-03464-w. Epub 2023 Mar 2.
Considering the rich background of Persian Medicine in the use of materia medica for the treatment of diseases, the huge burden of oral poisonings in the world, and the urgent need to find scientific solutions, the purpose of this study was to determine Avicenna's approach toward clinical toxicology and his proposed treatments for oral poisonings. In Al-Qanun Fi Al-Tibb, Avicenna addressed the materia medica for the treatments of oral poisonings after explaining the ingestion of different toxins and also elucidating the clinical toxicology approach toward poisoned patients. These materia medica were from different classes including emetics, purgatives, enemas, diaphoretics, antidiarrheals, inhaled drugs, sternutators, anticoagulants, antiepileptics, antitussives, diuretics, cooling drugs, stimulants, cardiotonic drugs, and heating oils. By applying different therapies, Avicenna endeavored to attain main goals in clinical toxicology that are comparable with modern medicine. They included removing the toxins from the body, decreasing the severity of the deleterious effects of toxins on the body, and counteracting the effects of toxins inside the body. Aside from introducing different therapeutic agents that played an important role in the treatment of oral poisonings, he emphasized the ameliorating effects of nutritive foods and beverages. Further research using other Persian medical resources is recommended to elucidate the applicable approaches and treatments for different poisonings.
鉴于波斯医学在使用药物治疗疾病方面的丰富背景、世界范围内口腔中毒的巨大负担,以及迫切需要寻找科学解决方案,本研究旨在确定阿维森纳(Avicenna)对临床毒理学的看法及其对口中毒的治疗方法。在《医典》中,阿维森纳在解释了不同毒素的摄入后,讨论了用于治疗口腔中毒的药物,并阐明了对中毒患者的临床毒理学方法。这些药物来自不同类别,包括催吐剂、泻药、灌肠剂、发汗剂、止泻剂、吸入性药物、喷嚏剂、抗凝剂、抗癫痫药、镇咳药、利尿剂、清凉药、兴奋剂、强心药和加热油。通过应用不同的疗法,阿维森纳努力实现了与现代医学相当的临床毒理学的主要目标。这些目标包括将毒素从体内排出、减轻毒素对身体的有害影响,以及抵消毒素在体内的作用。除了介绍在治疗口腔中毒方面发挥重要作用的不同治疗剂外,他还强调了营养食品和饮料的改善作用。建议进一步研究其他波斯医学资源,以阐明针对不同中毒的适用方法和治疗方法。