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萨比特·伊本·库拉对毒理学的贡献。

Ṯābit Ibn Qurra's contributions to toxicology.

作者信息

Amrollahi-Sharifabadi Mohammad, Musavi Seyed Esmaeil Ghasemi, Gholamifard Ali, Qoronfleh M Walid, Fawzy Marwa M M, Mohammed Sawsan G

机构信息

Department of Basic Sciences, Faculty of Veterinary Medicine, Lorestan University, Khorramabad, 68151-44316, Iran.

Department of Arabic Language and Literature, Faculty of Literature and Human Sciences, Lorestan University, Khorramabad, 68151-44316, Iran.

出版信息

Naunyn Schmiedebergs Arch Pharmacol. 2025 Jan;398(1):379-392. doi: 10.1007/s00210-024-03374-3. Epub 2024 Aug 23.

Abstract

Mankind has been familiar with poisons since ancient times. On the other hand, there is a wealth of knowledge in the medical books including medieval works of Middle Eastern polymaths such as Avicenna, "al-Rāzī," and "Ṯābit Ibn Qurra." This study presented and analyzed the knowledge of medical toxicology in one of the mainstay works of "Ṯābit Ibn Qurra" entitled "al-Ḏaḫira Fy Ꜥilm al-Tibb" also known as The Treasury of Medicine after the translation of the book from Arabic to English carefully and faithfully. Also, related toxicological literature was applied wherever required using English, Arabic, and Persian databases including Scopus, PubMed, Web of Science, WorldCat, Magiran, IranDoc, Scientific Information Database, Noor Mags, Noorlib, and Al Manhal. Our research revealed that chapter 25 of the mentioned book specifically focused on toxicology. This chapter was divided into sections on different aspects of toxicology from the categorization of poisons to compound mixtures causing poisonings to introducing blade poisons to signs and symptoms of poisonings, preventive approaches, and therapeutic agents. Specific antidotes and general therapies were introduced that included medicinal plants, cupping therapy, and bandages, just to name a few. Also, there were some monographs on the common poisonous agents and their treatments. The toxicological data of the book was comparable with modern toxicology. Our study highlighted the contributions of "Ṯābit Ibn Qurra" to medical toxicology by authoring The Treasury of Medicine. Further research is recommended to elucidate the full aspects of the history of toxicology including the contributions of the past scholars.

摘要

自古以来,人类就对毒药有所了解。另一方面,医学书籍中有着丰富的知识,包括中世纪中东博学者如阿维森纳、“拉齐”和“萨比特·伊本·库拉”的著作。本研究在仔细且忠实地将“萨比特·伊本·库拉”的一部重要著作《医学宝库》从阿拉伯语翻译成英语后,呈现并分析了其中的医学毒理学知识。此外,在需要的地方还应用了相关毒理学文献,使用了包括Scopus、PubMed、科学网、世界书目数据库、马吉兰数据库、伊朗文献数据库、科学信息数据库、努尔文献数据库、努尔图书馆数据库和艾尔·曼哈勒数据库在内的英语、阿拉伯语和波斯语数据库。我们的研究表明,上述书籍的第25章特别关注毒理学。该章分为多个部分,涉及毒理学的不同方面,从毒药的分类到导致中毒的复合混合物,再到介绍刀伤毒药、中毒的体征和症状、预防方法以及治疗药物。书中介绍了特定的解毒剂和一般疗法,包括药用植物、拔罐疗法和绷带等等。此外,还有一些关于常见有毒物质及其治疗方法的专题论文。该书的毒理学数据与现代毒理学相当。我们的研究突出了“萨比特·伊本·库拉”通过撰写《医学宝库》对医学毒理学的贡献。建议进一步开展研究,以阐明毒理学历史的各个方面,包括过去学者的贡献。

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