Department of Clinical Pharmacy, College of Pharmacy, University of Mosul, Ninevah, Iraq.
Georgian Med News. 2023 Jan(334):65-70.
Osteoarthritis (OA) is a chronic disease characterized by the collapse or destruction of the cartilage that covers the ends of the bone in the joints. Health-related quality of life (QoL) is a multidimensional concept that includes aspects of social, emotional, mental, and physical functioning. This study aimed to evaluate the quality of life among patients with OA. A cross-section study takes place in Mosul city with a sample of 370 patients aged 40 years and older included. The data collection form consisted of personnel with demographic and socioeconomic information, comprehension of the OA symptoms, and QoL scale. This study showed a significant relationship between QoL domains (domain 1 and domain 3) with age. Domain 1 shows a significant correlation with BMI and domain 3 also shows a significant correlation with the duration of the disease (p<.0.05). In addition to that gender show, significant differences in all QoL domains Glucosamine show significant differences in domain 1 and domain 3, also a significant difference in domain 3 with both steroid injection and hyaluronic injection in addition to the topical NSAIDs. Osteoarthritis is a disease that affects females more than males and causes poor quality of life. The intra- articular of both hyaluronic injection and steroid and Glucosamine had not been more beneficial and effective in the treatment of a group of patients with OA. WHOQOL-BRIF scale was valid for assessing the QoL among patients with osteoarthritis.
骨关节炎(OA)是一种慢性疾病,其特征是关节中骨头末端的软骨塌陷或破坏。健康相关生活质量(QoL)是一个多维概念,包括社会、情感、心理和身体功能等方面。本研究旨在评估 OA 患者的生活质量。在摩苏尔市进行了一项横断面研究,共纳入了 370 名年龄在 40 岁及以上的患者。数据收集表包括人口统计学和社会经济信息、对 OA 症状的理解以及 QoL 量表。本研究表明,QoL 领域(领域 1 和领域 3)与年龄之间存在显著关系。领域 1 与 BMI 呈显著相关,领域 3 与疾病持续时间也呈显著相关(p<.05)。此外,性别在所有 QoL 领域均存在显著差异,氨基葡萄糖在领域 1 和领域 3 中均有显著差异,在领域 3 中与甾体注射和透明质酸注射以及外用 NSAIDs 也有显著差异。OA 是一种女性比男性更易患病且生活质量较差的疾病。关节内注射透明质酸、甾体和氨基葡萄糖对一组 OA 患者的治疗并没有更有益和有效。WHOQOL-BRIF 量表可用于评估 OA 患者的生活质量。