护理模式与中医体质作为系统性硬化症患者抑郁和焦虑的影响因素：一项在新冠疫情期间的横断面研究
Care patterns and Traditional Chinese Medicine constitution as factors of depression and anxiety in patients with systemic sclerosis: A cross-sectional study during the COVID-19 pandemic.
作者信息
Kong Qi, Chen Li-Ming, Dai Zong-Hao, Tang Yun-Zhe, Zhou Yu-Yang, Tu Wen-Zhen, Zhao Yin-Huan, Zhang Jia-Qian
机构信息
Scientific Innovation Volunteer Team of Rare Diseases, Shanghai TCM-Integrated Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Putuo Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
出版信息
Front Integr Neurosci. 2023 Feb 14;17:1052683. doi: 10.3389/fnint.2023.1052683. eCollection 2023.
OBJECTIVE
Care patterns and Traditional Chinese Medicine (TCM) constitution affects the emotion and health of patients with systemic sclerosis (SSc) while the prevalence of COVID-19 may aggravate such patients' emotion and health. We investigated the depression and anxiety levels of patients with SSc during the pandemic to identify the correlation between care patterns, TCM constitution, and patients' emotion.
MATERIALS AND METHODS
This was a cross-sectional study. Patients with SSc and healthy individuals were surveyed using the patient health questionnaire-9, generalized anxiety disorder-7, and constitution in Chinese medicine questionnaire and a modified care pattern questionnaire. Factors correlated with depression and anxiety were screened using univariate and multivariate logistic regression analyses.
RESULTS
A total of 273 patients with SSc and 111 healthy individuals were included in the analysis. The proportion of patients with SSc who were depressed was 74.36%, who had anxiety was 51.65%, and who experienced disease progression during the pandemic was 36.99%. The proportion of income reduction in the online group (56.19%) was higher than that in the hospital group (33.33%) ( = 0.001). Qi-deficiency [adjusted odds ratio (OR) = 2.250] and Qi-stagnation (adjusted OR = 3.824) constitutions were significantly associated with depression. Remote work during the outbreak (adjusted OR = 1.920), decrease in income (adjusted OR = 3.556), and disease progression ( = 0.030) were associated with the occurrence of depression.
CONCLUSION
Chinese patients with SSc have a high prevalence of depression and anxiety. The COVID-19 pandemic has changed the care patterns of Chinese patients with SSc, and work, income, disease progression, and change of medications were correlates of depression or anxiety in patients with SSc. Qi-stagnation and Qi-deficiency constitutions were associated with depression, and Qi-stagnation constitution was associated with anxiety in patients with SSc.
TRIAL REGISTRATION
http://www.chictr.org.cn/showproj.aspx?proj=62301, identifier ChiCTR2000038796.
目的
护理模式和中医体质会影响系统性硬化症（SSc）患者的情绪和健康，而新型冠状病毒肺炎（COVID-19）的流行可能会加重此类患者的情绪和健康问题。我们调查了疫情期间SSc患者的抑郁和焦虑水平，以确定护理模式、中医体质与患者情绪之间的相关性。
材料与方法
这是一项横断面研究。使用患者健康问卷9、广泛性焦虑障碍量表7、中医体质问卷和改良的护理模式问卷对SSc患者和健康个体进行调查。采用单因素和多因素逻辑回归分析筛选与抑郁和焦虑相关的因素。
结果
共纳入273例SSc患者和111例健康个体进行分析。SSc患者中抑郁的比例为74.36%，焦虑的比例为51.65%，疫情期间病情进展的比例为36.99%。线上组收入减少的比例（56.19%）高于线下组（33.33%）（P = 0.001）。气虚体质（调整优势比[OR]=2.250）和气郁体质（调整OR = 3.824）与抑郁显著相关。疫情期间远程工作（调整OR = 1.920）、收入减少（调整OR = 3.556）和病情进展（P = 0.030）与抑郁的发生有关。
结论
中国SSc患者抑郁和焦虑的患病率较高。COVID-19疫情改变了中国SSc患者的护理模式，工作、收入、病情进展和药物变化是SSc患者抑郁或焦虑的相关因素。气郁体质和气虚体质与SSc患者的抑郁有关，气郁体质与SSc患者的焦虑有关。
试验注册
http://www.chictr.org.cn/showproj.aspx?proj=62301，标识符ChiCTR2000038796 。
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