Bemis Kylie Ariel, Föll Melanie Christine, Guo Dan, Lakkimsetty Sai Srikanth, Vitek Olga
Khoury College of Computer Sciences, Northeastern University, Boston, USA.
Institute of Surgical Pathology, Medical Center - University of Freiburg, Faculty of Medicine, Freiburg, Germany.
bioRxiv. 2023 Feb 21:2023.02.20.529280. doi: 10.1101/2023.02.20.529280.
Cardinal v3 is an open source software for reproducible analysis of mass spectrometry imaging experiments. A major update from its previous versions, Cardinal v3 supports most mass spectrometry imaging workflows. Its analytical capabilities include advanced data processing such as mass re-calibration, advanced statistical analyses such as single-ion segmentation and rough annotation-based classification, and memory-efficient analyses of large-scale multi-tissue experiments.
Cardinal v3是一款用于质谱成像实验可重复分析的开源软件。作为其先前版本的重大更新,Cardinal v3支持大多数质谱成像工作流程。其分析功能包括高级数据处理(如质量重新校准)、高级统计分析(如单离子分割和基于粗略注释的分类)以及对大规模多组织实验的内存高效分析。