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Cardinal v3 - 一款用于质谱成像分析的多功能开源软件。

Cardinal v3 - a versatile open source software for mass spectrometry imaging analysis.

作者信息

Bemis Kylie Ariel, Föll Melanie Christine, Guo Dan, Lakkimsetty Sai Srikanth, Vitek Olga

机构信息

Khoury College of Computer Sciences, Northeastern University, Boston, USA.

Institute of Surgical Pathology, Medical Center - University of Freiburg, Faculty of Medicine, Freiburg, Germany.

出版信息

bioRxiv. 2023 Feb 21:2023.02.20.529280. doi: 10.1101/2023.02.20.529280.

Abstract

Cardinal v3 is an open source software for reproducible analysis of mass spectrometry imaging experiments. A major update from its previous versions, Cardinal v3 supports most mass spectrometry imaging workflows. Its analytical capabilities include advanced data processing such as mass re-calibration, advanced statistical analyses such as single-ion segmentation and rough annotation-based classification, and memory-efficient analyses of large-scale multi-tissue experiments.

摘要

Cardinal v3是一款用于质谱成像实验可重复分析的开源软件。作为其先前版本的重大更新,Cardinal v3支持大多数质谱成像工作流程。其分析功能包括高级数据处理(如质量重新校准)、高级统计分析(如单离子分割和基于粗略注释的分类)以及对大规模多组织实验的内存高效分析。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f855/9980127/49b6c2c9568f/nihpp-2023.02.20.529280v1-f0001.jpg

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