Khoury College of Computer Sciences, Northeastern University, Boston, MA, USA.
Institute of Surgical Pathology, Medical Center, University of Freiburg, Faculty of Medicine, Freiburg, Germany.
Nat Methods. 2023 Dec;20(12):1883-1886. doi: 10.1038/s41592-023-02070-z. Epub 2023 Nov 23.
Cardinal v.3 is an open-source software for reproducible analysis of mass spectrometry imaging experiments. A major update from its previous versions, Cardinal v.3 supports most mass spectrometry imaging workflows. Its analytical capabilities include advanced data processing such as mass recalibration, advanced statistical analyses such as single-ion segmentation and rough annotation-based classification, and memory-efficient analyses of large-scale multitissue experiments.
Cardinal v.3 是一款用于可重复分析质谱成像实验的开源软件。相较于其前几个版本，Cardinal v.3 是一个重大更新，支持大多数质谱成像工作流程。其分析功能包括高级数据处理，如质量重新校准、高级统计分析，如单离子分割和基于粗略注释的分类，以及对大规模多组织实验的高效内存分析。
