Katano Atsuto, Nozawa Yuki, Imae Toshikazu, Yamashita Hideomi, Nakagawa Keiichi
Radiology, The University of Tokyo Hospital, Tokyo, JPN.
Department of Comprehensive Radiation Oncology, The University of Tokyo, Tokyo, JPN.
Cureus. 2023 Jan 29;15(1):e34347. doi: 10.7759/cureus.34347. eCollection 2023 Jan.
Radiation therapy plays an important role in cancer treatment along with surgery and systemic therapy. The total dose of radiation therapy is divided into small doses, and the treatment is typically delivered once a day. The total treatment period can need several weeks or more, and it is necessary to deliver the radiation dose to the target volume within the patient precisely each time. Therefore, the reproducibility of patient positioning is essential for the precision of the dose delivery. Although radiological technologies such as image-guided radiation therapy have also recently been widely used for positioning patients, skin marking is still widely used in many facilities. Skin marking is an inexpensive and universal positioning technique in patients undergoing radiation therapy; however, it is considered a major source of psychological stress. We propose the use of fluorescent ink pens, which are invisible in standard room lighting, as skin markers for radiotherapy. The primary technique of fluorescence emission is widely employed in molecular biological experiments and for assessing cleaning protocols for infection control. This technique may reduce the stress induced by skin markings during radiotherapy.
放射治疗与手术和全身治疗一起在癌症治疗中发挥着重要作用。放射治疗的总剂量被分成小剂量，并且治疗通常每天进行一次。整个治疗周期可能需要数周或更长时间，而且每次都必须将辐射剂量精确地输送到患者体内的靶区。因此，患者定位的可重复性对于剂量输送的精确性至关重要。尽管诸如图像引导放射治疗等放射技术最近也被广泛用于患者定位，但皮肤标记在许多机构中仍被广泛使用。皮肤标记是接受放射治疗患者的一种廉价且通用的定位技术；然而，它被认为是心理压力的一个主要来源。我们提议使用在标准室内照明下不可见的荧光墨水笔作为放射治疗的皮肤标记物。荧光发射的主要技术在分子生物学实验以及评估感染控制清洁方案中被广泛应用。该技术可能会减轻放射治疗期间皮肤标记所引发的压力。
