Lacy Brian E, Cangemi David J, Spiegel Brennan R
Division of Gastroenterology & Hepatology, Mayo Clinic, Jacksonville, Florida.
Division of Health Sciences Research, Department of Medicine, Cedars-Sinai Health System, Los Angeles, California.
Gastroenterol Hepatol (N Y). 2023 Feb;19(2):86-94.
Disorders of gut-brain interaction (DGBIs), previously called functional bowel disorders, are prevalent, reduce patients' quality of life, and impose a significant negative economic impact on the health care system. Functional dyspepsia and irritable bowel syndrome (IBS) are 2 of the most common DGBIs. An overlying, and in many cases unifying, symptom for many of these disorders is the presence of abdominal pain. Chronic abdominal pain can be difficult to treat, as many antinociceptive agents are associated with side effects that limit their use and other agents may only partially improve, but not completely relieve, all aspects of the pain. Novel therapies to alleviate chronic pain and the other symptoms that characterize DGBIs are thus needed. Virtual reality (VR), a technology that immerses patients in a multisensory experience, has been shown to relieve pain in burn victims and other instances of somatic pain. Two recent novel studies have demonstrated that VR has the potential to play an important role in the treatment of functional dyspepsia and IBS. This article examines the development of VR, its role in the treatment of somatic and visceral pain, and its potential position in the treatment of DGBIs.
肠脑互动障碍（DGBIs），以前称为功能性肠病，很常见，会降低患者的生活质量，并对医疗保健系统造成重大的负面经济影响。功能性消化不良和肠易激综合征（IBS）是最常见的两种DGBIs。这些疾病中许多都存在的一个共同且在很多情况下具有统一性的症状是腹痛。慢性腹痛可能难以治疗，因为许多镇痛药物都有副作用，限制了它们的使用，而其他药物可能只能部分改善疼痛的各个方面，但不能完全缓解疼痛。因此，需要新的疗法来缓解慢性疼痛以及DGBIs的其他特征性症状。虚拟现实（VR）是一种让患者沉浸在多感官体验中的技术，已被证明可以减轻烧伤患者的疼痛以及其他躯体疼痛情况。最近的两项新研究表明，VR在功能性消化不良和IBS的治疗中具有发挥重要作用的潜力。本文探讨了VR的发展、其在躯体和内脏疼痛治疗中的作用以及在DGBIs治疗中的潜在地位。
