Simsek M Fethullah, Özbudak Ertuğrul M
Division of Developmental Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.
Division of Developmental Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH 45229, USA.
Cell Stem Cell. 2023 Mar 2;30(3):246-247. doi: 10.1016/j.stem.2023.01.011.
In vitro models to study human somitogenesis, the formation of the segmented body plan, have so far been limited. Two papers in Nature now report the creation of pluripotent stem cell (PSC)-derived 3D culture systems that recapitulate the formation of somite-like structures and help gain insights into this developmental process..
迄今为止，用于研究人类体节发生（即分段身体结构的形成）的体外模型一直很有限。《自然》杂志上的两篇论文如今报道了多能干细胞（PSC）衍生的3D培养系统的创建，该系统概括了体节样结构的形成，并有助于深入了解这一发育过程。
