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[弥漫性硬化症中的抗病毒免疫]

[Antiviral immunity in disseminated sclerosis].

作者信息

Khaletskaia E V, Fadeeva L L, Priĭmiagi L S, Luka V Ia

出版信息

Vopr Virusol. 1987 Jul-Aug;32(4):438-40.

PMID:3686983
Abstract

Titres of antibodies to various viral antigens, levels of immunoglobulins, and the rate of detection of specific IgM to measles virus were studied in the blood sera of 50 patients with multiple sclerosis and 50 normal subjects. High antibody titres to measles, mumps, rubella and parainfluenza type 3 virus antigens were revealed. Specific IgM to measles virus were detected in 50% of multiple sclerosis patients and in none of the normal subjects. The patients with multiple sclerosis showed no significant differences in the levels of immunoglobulins of the three main classes (G, A, M).

摘要

对50例多发性硬化症患者和50名正常受试者的血清进行了研究,检测了其针对各种病毒抗原的抗体滴度、免疫球蛋白水平以及麻疹病毒特异性IgM的检出率。结果发现,针对麻疹、腮腺炎、风疹和3型副流感病毒抗原的抗体滴度较高。50%的多发性硬化症患者检测到麻疹病毒特异性IgM,而正常受试者中均未检测到。多发性硬化症患者的三类主要免疫球蛋白(G、A、M)水平无显著差异。

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