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糖化血清蛋白测定:硫代巴比妥酸法与果糖胺法的比较

Glycated serum protein determination: comparison between thiobarbituric acid and fructosamine assays.

作者信息

Poli T, Lapolla A, Plebani M, Franchin A, Fedele D

机构信息

Istituto di Medicina Interna, Padova, Italy.

出版信息

Acta Diabetol Lat. 1987 Jul-Sep;24(3):241-7. doi: 10.1007/BF02732043.

Abstract

Glycated serum proteins were evaluated with fructosamine (GSP-fructosamine) and thiobarbituric acid (GSP) assays in 60 normal and 60 diabetic subjects. Higher levels of GSP-fructosamine and GSP were found in diabetics in comparison to controls. GSP-fructosamine levels were positively related to GSP values and the other metabolic control parameters. Moreover, the fructosamine assay is sensitive, reproducible, rapid and easy to perform. Thus, fructosamine assay could be a useful method for glycated serum protein evaluation in diabetic patients.

摘要

采用果糖胺法(GSP-果糖胺)和硫代巴比妥酸法(GSP)对60例正常人和60例糖尿病患者的糖化血清蛋白进行了评估。与对照组相比,糖尿病患者的GSP-果糖胺和GSP水平更高。GSP-果糖胺水平与GSP值及其他代谢控制参数呈正相关。此外,果糖胺检测方法灵敏、可重复、快速且易于操作。因此,果糖胺检测可能是评估糖尿病患者糖化血清蛋白的一种有用方法。

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