Zhang Kun, Wang Lijie, Peng Jiayan, Sangji Kangzhuo, Luo Yuting, Zeng Yujiao, Zeweng Yongzhong, Fan Gang
State Key Laboratory of Southwestern Chinese Medicine Resources, School of Ethnic Medicine, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Front Pharmacol. 2023 Feb 16;14:1098253. doi: 10.3389/fphar.2023.1098253. eCollection 2023.
The Coronavirus Diseases 2019 (COVID-19) has been rapidly spreading globally and has caused severe harm to the health of people and a substantial social burden. In response to this situation, experts around the world have considered various treatments, including the use of traditional medicine. Traditional Tibetan medicine (TTM), one of the traditional medicines in China, has played an important role in the treatment of infectious diseases in history. It has formed a solid theoretical foundation and accumulated rich experience in the treatment of infectious diseases. In this review, we provide a comprehensive introduction to the basic theory, treatment strategies, and commonly used drugs of TTM for the treatment of COVID-19. In addition, the efficacies and potential mechanisms of these TTM drugs against COVID-19 are discussed based on available experimental data. This review may provide important information for the basic research, clinical application and drug development of traditional medicines for the treatment of COVID-19 or other infectious diseases. More pharmacological studies are needed to reveal the therapeutic mechanisms and active ingredients of TTM drugs in the treatment of COVID-19.
2019年冠状病毒病(COVID-19)已在全球迅速传播,对人们的健康造成了严重危害,并带来了沉重的社会负担。针对这一情况,世界各地的专家考虑了各种治疗方法,包括使用传统医学。藏医药作为中国传统医学之一,在历史上的传染病治疗中发挥了重要作用。它在传染病治疗方面形成了坚实的理论基础,并积累了丰富的经验。在本综述中,我们全面介绍了藏医药治疗COVID-19的基本理论、治疗策略和常用药物。此外,还根据现有实验数据讨论了这些藏医药药物抗COVID-19的疗效和潜在机制。本综述可能为治疗COVID-19或其他传染病的传统药物的基础研究、临床应用和药物开发提供重要信息。需要更多的药理学研究来揭示藏医药药物治疗COVID-19的治疗机制和活性成分。