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（C. B. 克拉克）赫克的传统用途、植物化学、药理学及毒理学综述

Traditional uses, phytochemistry, pharmacology, and toxicology of (C. B. Clarke) Höeck: a review.

作者信息

Gan Zhiqiang, Jiang Juan, Tao Honglin, Luo Shiying, Meng Xianli, Yu Jia, Zhang Yi, Tang Ce

机构信息

School of Pharmacy, Chengdu University of Traditional Chinese Medicine Chengdu 611137 China.

Chongqing University Cancer Hospital Chongqing 400030 China.

出版信息

RSC Adv. 2021 Aug 26;11(46):28761-28774. doi: 10.1039/d1ra05548h. eCollection 2021 Aug 23.

DOI:10.1039/d1ra05548h
PMID:35478563
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9038101/
Abstract

(C. B. Clarke) Höeck is a member of the Dipsacaceae family and has been used in traditional Tibetan medicine for thousands of years. clears heat, detoxifies, stops dysentery, eliminates distemper, dispels wind, and relieves stagnation and is mainly prescribed for heat syndrome, dysentery, arthritis, and plague. Approximately 93 chemical compounds have been isolated and identified from , including iridoid glycosides, lignan and triterpenoids. Meanwhile, modern pharmacological studies have shown that has anti-inflammatory, anti-rheumatoid arthritis, analgesic, anticancer, and neuroprotection activities. However, studies on the pharmacokinetics and mechanism of action, discovery of quality markers, and qualitative and quantitative analysis are still insufficient. Hence, this paper provides a comprehensive review of the ethnic medicine, phytochemistry, pharmacology, and toxicology of to increase the understanding of the medicinal value of

摘要

（C.B.克拉克）匙叶草是川续断科的一员，在传统藏药中已使用了数千年。它能清热、解毒、止痢、除瘟、祛风、理气，主要用于治疗热证、痢疾、关节炎和瘟疫。从匙叶草中已分离并鉴定出约93种化合物，包括环烯醚萜苷、木脂素和三萜类化合物。同时，现代药理学研究表明，匙叶草具有抗炎、抗类风湿性关节炎、镇痛、抗癌和神经保护活性。然而，关于匙叶草的药代动力学和作用机制、质量标志物的发现以及定性和定量分析的研究仍然不足。因此，本文对匙叶草的民族医学、植物化学、药理学和毒理学进行了全面综述，以增进对其药用价值的了解 。

需注意，原文中存在一些指代不明的地方，比如多次出现“ ”，可能影响准确理解，但按照要求进行了翻译。

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