Kanai N, Nagaki S, Tanaka T
Division of Pathology and Internal Medicine, Takayama Red Cross Hospital, Gifu, Japan.
Acta Pathol Jpn. 1987 Sep;37(9):1521-6. doi: 10.1111/j.1440-1827.1987.tb02273.x.
A rare autopsy case of clear cell carcinoma of the pancreas developing in a 71-year-old Japanese male is described. He complained of epigastralgia and back pain and was clinically diagnosed as having primary pancreatic cancer. After death due to disseminated metastasis and cachexy, autopsy revealed pancreatic clear cell carcinoma metastasizing to various organs including the lungs (lymphoangiosis carcinomatosa). The tumor was almost entirely composed of clear cells with cytoplasm weakly positive for PAS and alcian blue, and negative for Sudan III stains. Histological differential diagnosis from the clear cell carcinoma of other organs, especially that of kidney, is also mentioned.
本文描述了一例罕见的胰腺透明细胞癌尸检病例，患者为一名71岁的日本男性。他主诉上腹部疼痛和背痛，临床诊断为原发性胰腺癌。在因广泛转移和恶病质死亡后，尸检发现胰腺透明细胞癌已转移至包括肺在内的多个器官（淋巴管癌病）。肿瘤几乎完全由透明细胞组成，其细胞质对PAS和阿尔辛蓝呈弱阳性，对苏丹III染色呈阴性。文中还提及了与其他器官尤其是肾脏的透明细胞癌进行组织学鉴别诊断的情况。
