Wang Wei, Gong Zhihao, Zhao Mingye, Zhang Zuojing, Qiu Yuwei, Jiang Qiliang, Wu Jingxiang
Department of Anesthesiology, Shanghai Chest Hospital, Shanghai Jiao Tong University, School of Medicine, Shanghai, China.
Front Surg. 2023 Feb 17;10:1090233. doi: 10.3389/fsurg.2023.1090233. eCollection 2023.
Malposition of the double-lumen tubes (DLTs) may lead to hypoxemia during one-lung ventilation (OLV). Video double-lumen tubes (VDLTs) enable continuous observation of DLT position and avoid displacement. We aimed to investigate whether VDLTs could reduce the incidence of hypoxemia during OLV compared with conventional double-lumen tubes (cDLT) in thoracoscopic lung resection surgery.
This was a retrospective cohort study. Adult patients who underwent elective thoracoscopic lung resection surgery and required VDLTs or cDLTs for OLV at Shanghai Chest Hospital from January 2019 to May 2021 were included. The primary outcome was the incidence of hypoxemia during OLV between VDLT and cDLT. Secondary outcomes included bronchoscopy use, the degree of PaO decline, and arterial blood gas indices.
A total of 1,780 patients were finally analyzed in propensity score-matched cohorts (VDLT vs. cDLT 1:1 = 890). The incidence of hypoxemia decreased from 6.5% (58/890) in cDLT group to 3.6% (32/890) in VDLT group (Relative Risk [RR]: 1.812, 95% CI: 1.19-2.76, = 0.005). The use of bronchoscopy was reduced by 90% in VDLT group (VDLT 10.0% (89/890) vs. cDLT 100% (890/890), < 0.001). PaO after OLV was 221 [136.0-325.0] mmHg in cDLT group compared to 234 [159.7-336.2] mmHg in VDLT group, = 0.003. The percentage of PaO decline was 41.4 [15.4-61.9] % in cDLT group, while it was 37.7 [8.7-55.9] % in the VDLT group, < 0.001. In patients who suffered from hypoxemia, there were no significant differences in arterial blood gas indices or the percentage of PaO decline.
VDLTs reduce the incidence of hypoxemia and the use of bronchoscopy during OLV compared with cDLTs. VDLT may be a feasible option for thoracoscopic surgery.
双腔气管导管(DLT)位置不当可能导致单肺通气(OLV)期间出现低氧血症。可视双腔气管导管(VDLT)能够持续观察DLT位置并避免移位。我们旨在研究在胸腔镜肺切除手术中,与传统双腔气管导管(cDLT)相比,VDLT是否能降低OLV期间低氧血症的发生率。
这是一项回顾性队列研究。纳入2019年1月至2021年5月在上海胸科医院接受择期胸腔镜肺切除手术且OLV需要VDLT或cDLT的成年患者。主要结局是VDLT组和cDLT组OLV期间低氧血症的发生率。次要结局包括支气管镜的使用、PaO下降程度和动脉血气指标。
倾向评分匹配队列(VDLT与cDLT 1:1 = 890)中最终共分析了1780例患者。低氧血症发生率从cDLT组的6.5%(58/890)降至VDLT组的3.6%(32/890)(相对风险[RR]:1.812,95%可信区间:1.19 - 2.76,P = 0.005)。VDLT组支气管镜的使用减少了90%(VDLT 1D.0%(89/890)对cDLT 100%(890/890),P < 0.001)。OLV后cDLT组的PaO为221[136.0 - 325.0]mmHg,而VDLT组为234[159.7 - 336.2]mmHg,P = 0.003。cDLT组PaO下降百分比为41.4[15.4 - 61.9]%,而VDLT组为37.7[8.7 - 55.9]%,P < 0.001。在发生低氧血症的患者中,动脉血气指标或PaO下降百分比无显著差异。
与cDLT相比,VDLT降低了OLV期间低氧血症的发生率和支气管镜的使用。VDLT可能是胸腔镜手术的一个可行选择。