Tan Yingyao, Qin Meijiao, Liao Bing, Wang Lixia, Chang Guangting, Wei Fengxiang, Cai Shu
School of Nursing, Guangdong Pharmaceutical University, Guangdong, China.
Longgang District Maternity and Child Healthcare Hospital of Shenzhen City, Shenzhen, China.
Breast Care (Basel). 2023 Feb;18(1):49-59. doi: 10.1159/000527849. Epub 2022 Nov 25.
Breast cancer patients report high levels of psychosocial maladjustment after hospital discharge. Peer support may play an important role in improving anxiety and quality of life in breast cancer patients. This study aimed to assess the effect of peer support on quality of life and anxiety in breast cancer patients.
A systematic review and meta-analysis of randomized controlled studies were conducted, using data sourced from PubMed, Embase, Cochrane Central Register of Controlled Trials, Web of Science, SinoMed, China Science and Technology Periodical Database, China National Knowledge Infrastructure, and Wanfang Data for randomized controlled trials (RCTs) from inception to October 15, 2021. The RCTs reporting the effect of peer support intervention on quality of life and anxiety in breast cancer patients were included. The quality of evidence was assessed using the Cochrane risk of bias tool, that is, the Grading of Recommendations Assessment, Development, and Evaluation (GRADE). Standardized mean differences (SMDs) and 95% confidence intervals (CIs) were calculated for the pooled effect size.
A total of 14 studies were included in the systematic review and 11 in the meta-analysis. The pooled results revealed that peer support significantly improved quality of life (SMD = 0.69, 95% CI = 0.28-1.11) and anxiety (SMD = -0.45, 95% CI = -0.88 to -0.02) in breast cancer patients. The quality of evidence was low as all studies showed the risk of bias and inconsistency.
Peer support intervention has the potential to effectively improve psychosocial adaptations in breast cancer patients. Future studies with a robust design and larger sample size are needed to investigate the potential factors associated with the beneficial effects of peer support.
乳腺癌患者出院后报告有高水平的心理社会适应不良。同伴支持可能在改善乳腺癌患者的焦虑和生活质量方面发挥重要作用。本研究旨在评估同伴支持对乳腺癌患者生活质量和焦虑的影响。
对随机对照研究进行系统评价和荟萃分析，数据来源于PubMed、Embase、Cochrane对照试验中心注册库、Web of Science、中国生物医学文献数据库、中国科技期刊数据库、中国知网和万方数据，检索从开始到2021年10月15日的随机对照试验（RCT）。纳入报告同伴支持干预对乳腺癌患者生活质量和焦虑影响的RCT。使用Cochrane偏倚风险工具，即推荐分级评估、制定和评价（GRADE）来评估证据质量。计算合并效应量的标准化均数差（SMD）和95%置信区间（CI）。
系统评价共纳入14项研究，荟萃分析纳入11项研究。汇总结果显示，同伴支持显著改善了乳腺癌患者的生活质量（SMD = 0.69，95% CI = 0.28 - 1.11）和焦虑（SMD = -0.45，95% CI = -0.88至 -0.02）。由于所有研究均显示存在偏倚风险和不一致性，证据质量较低。
同伴支持干预有可能有效改善乳腺癌患者的心理社会适应情况。需要未来进行设计更严谨、样本量更大的研究，以探究与同伴支持有益效果相关的潜在因素。
