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巨大肝包虫囊肿累及膈肌、心包和肝脏:体外循环在大肝切除术中的应用:病例报告及文献复习。

Giant Hydatid Cyst with Diaphragmatic, Pericardial, and Hepatic Involvement: Use of Extracorporeal Circulation for Major Liver Resection: A Case Report and Literature Review.

机构信息

School of Medicine, Universidad del Rosario, Bogotá, Colombia.

School of Medicine, Pontificia Universidad Javeriana, Bogotá, CO, Colombia.

出版信息

Am J Case Rep. 2023 Mar 6;24:e938601. doi: 10.12659/AJCR.938601.

DOI:10.12659/AJCR.938601
PMID:36876895
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10000324/
Abstract

BACKGROUND Echinococcosis is a zoonosis caused by the echinococcus microorganism, a parasite with 6 described species in the literature, the main one in humans being Echinococcus granulosus. Transmission is via the fecal-oral route, with main hepatopulmonary involvement but with high risk of dissemination. Diagnosis is often incidental and patients present a wide range of non-specific symptoms, closely related to localization, size, and quantity of cysts. The latent risk of the infection is septic shock secondary to intraperitoneal rupture, which increases the risk of mortality. The criterion standard of management involves anthelmintic therapy and radical surgical management. CASE REPORT We present the case of a man in the third decade of life from a rural area of Colombia, presenting abdominal pain and febrile peaks for 2 months. Imaging studies showed a cystic lesion with thoracic and hepatic involvement. He was treated in 2 surgical stages, the first achieving partial resection of the cyst involving lung, diaphragm, and rib cage, and the second with extracorporeal circulation assistance due to infiltration of the retrohepatic vena cava, achieving radical resection of the disease. CONCLUSIONS Echinococcosis is a condition endemic to rural areas, with wide geographical distribution. Given the slow growth, it is mostly asymptomatic, which causes diagnostic and therapeutic challenges involving high rates of complications and mortality. An individualized surgical and medical approach is recommended. Extracorporeal circulation assistance helps achieve hemodynamic stability in patients with cardiac or great vessel involvement. To the best of our knowledge, this is the first report of extracorporeal circulation assistance for large hepatic-diaphragmatic and pericardial cyst resection.

摘要

背景

包虫病是一种由棘球蚴微生物引起的人畜共患疾病,该寄生虫在文献中有 6 个描述物种,在人类中主要是细粒棘球蚴。传播途径为粪-口途径,主要涉及肝肺,但有很高的播散风险。诊断通常是偶然的,患者表现出广泛的非特异性症状,与囊肿的定位、大小和数量密切相关。感染的潜在风险是由于腹腔内破裂引起的败血性休克,这增加了死亡率。管理的标准准则包括驱虫治疗和根治性手术管理。

病例报告

我们介绍了一名来自哥伦比亚农村地区的 30 多岁男子的病例,他有腹痛和发热高峰 2 个月。影像学研究显示有一个胸肝受累的囊性病变。他接受了 2 个手术阶段的治疗,第一阶段实现了肺、膈肌和肋骨笼部分切除的囊切除术,第二阶段由于肝后腔静脉浸润,在外周体外循环辅助下实现了根治性疾病切除。

结论

包虫病是一种农村地区流行的疾病,具有广泛的地理分布。由于生长缓慢,它大多无症状,这导致了诊断和治疗的挑战,涉及高并发症和死亡率。建议采用个体化的手术和医疗方法。体外循环辅助有助于在心脏或大血管受累的患者中实现血流动力学稳定。据我们所知,这是首例报告体外循环辅助用于大肝膈肌和心包囊肿切除术。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed58/10000324/9e1720b8c1cd/amjcaserep-24-e938601-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed58/10000324/e1e20b8d5efe/amjcaserep-24-e938601-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed58/10000324/175e00292ad8/amjcaserep-24-e938601-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed58/10000324/b1b14641a604/amjcaserep-24-e938601-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed58/10000324/4ef3c29bdc6c/amjcaserep-24-e938601-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed58/10000324/4bad206ae7ec/amjcaserep-24-e938601-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed58/10000324/0a2520eecf37/amjcaserep-24-e938601-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed58/10000324/424e3c263d7b/amjcaserep-24-e938601-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed58/10000324/9e1720b8c1cd/amjcaserep-24-e938601-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed58/10000324/e1e20b8d5efe/amjcaserep-24-e938601-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed58/10000324/175e00292ad8/amjcaserep-24-e938601-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed58/10000324/b1b14641a604/amjcaserep-24-e938601-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed58/10000324/4ef3c29bdc6c/amjcaserep-24-e938601-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed58/10000324/4bad206ae7ec/amjcaserep-24-e938601-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed58/10000324/0a2520eecf37/amjcaserep-24-e938601-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed58/10000324/424e3c263d7b/amjcaserep-24-e938601-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed58/10000324/9e1720b8c1cd/amjcaserep-24-e938601-g008.jpg

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本文引用的文献

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The Molecular Epidemiology of Infections.感染的分子流行病学
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Hepatic hydatid cyst - diagnose and treatment algorithm.肝包虫囊肿——诊断与治疗流程
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Hepatobiliary and Pancreatic: Massive hepatic cystic echinococcosis compressing inferior vena cava.肝胆胰:巨大肝囊性包虫病压迫下腔静脉。
儿童呼吸困难的罕见病因:棘球蚴所致的包虫囊肿。
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