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感染的分子流行病学

The Molecular Epidemiology of Infections.

作者信息

Thompson R C Andrew

机构信息

School of Veterinary and Life Sciences, Murdoch University, Murdoch, WA 6150, Australia.

出版信息

Pathogens. 2020 Jun 8;9(6):453. doi: 10.3390/pathogens9060453.

Abstract

Molecular epidemiology (ME) is the application of molecular tools to determine the causation of disease. With infectious diseases, such as echinococcosis, this applies to identifying and characterising the aetiological agents and elucidating host range. Such an approach has been very successful with the causative agents of echinococcosis, species of , initially by providing a workable and practical taxonomy and subsequently determining transmission patterns in endemic areas. This review summarises the taxonomy and nomenclature of species of and provides an update on ME investigations of the ecology of transmission, particularly in areas where more than one species of is maintained in cycles of transmission that may interact.

摘要

分子流行病学(ME)是应用分子工具来确定疾病病因的学科。对于诸如棘球蚴病等传染病,这适用于识别和表征病原体以及阐明宿主范围。这种方法在棘球蚴病的病原体( 属的物种)研究中非常成功,最初是通过提供可行且实用的分类学,随后确定流行地区的传播模式。本综述总结了 属物种的分类学和命名法,并提供了关于 传播生态学的分子流行病学调查的最新情况,特别是在有不止一种 属物种在可能相互作用的传播循环中维持的地区。

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