Center for Cancer Biology, Immunology and Infection, Chicago Medical School, Rosalind Franklin University of Medicine and Science, North Chicago, IL, 60064, USA.
Mil Med Res. 2023 Mar 8;10(1):11. doi: 10.1186/s40779-023-00449-9.
Gulf War Illness (GWI) encompass a spectrum of maladies specific to troops deployed during the Persian Gulf War (1990-1991). There are several hypothesized factors believed to contribute to GWI, including (but not limited to) exposures to chemical agents and a foreign environment (e.g., dust, pollens, insects, and microbes). Moreover, the inherent stress associated with deployment and combat has been associated with GWI. While the etiology of GWI remains uncertain, several studies have provided strong evidence that chemical exposures, especially neurotoxicants, may be underlying factors for the development of GWI. This mini style perspective article will focus on some of the major evidence linking chemical exposures to GWI development and persistence decades after exposure.
海湾战争病（GWI）包括在海湾战争（1990-1991 年）期间部署的部队特有的一系列疾病。有几个假设的因素被认为与 GWI 有关，包括（但不限于）接触化学制剂和外国环境（例如灰尘、花粉、昆虫和微生物）。此外，与部署和战斗相关的内在压力也与 GWI 有关。虽然 GWI 的病因仍不确定，但多项研究提供了有力的证据表明，化学暴露，尤其是神经毒性物质，可能是 GWI 发展的潜在因素。这篇迷你风格的观点文章将重点介绍一些主要证据，这些证据将化学暴露与 GWI 的发展和数十年后的持续性联系起来。
