Jayalakshmi Sita, Telugu Ramakrishna, Vooturi Sudhindra, Patil Anuja, Sirisha Sai, Somayajula Shanmukhi
Department of Neurology, Krishna Institute of Medical Sciences, Secunderabad, Telangana, India.
J Neurosci Rural Pract. 2023 Jan-Mar;14(1):111-118. doi: 10.25259/JNRP-2022-6-40. Epub 2022 Nov 2.
Effect of psychological disorders on social functioning in people with epilepsy (PWE) is not extensively reported. We evaluate psychosocial functioning in PWE attending an outpatient clinic and aim to understand the differences in psychosocial functioning between anxiety, depression, and coexisting anxiety and depression in PWE.
A prospective evaluation of psychosocial functioning of 324 consecutive adult PWE attending outpatient epilepsy clinic was done using self-reported Washington Psychosocial Seizure Inventory. The study population was divided in four groups - without psychological disorders, anxiety, depression, and both anxiety and depression.
The mean age of study population was 25.90 ± 6.22 years. Anxiety was noted in 73 (22.5%), depression in 60 (18.5%), and both anxiety and depression were seen in 70 (21.6%) and the rest had normal psychosocial function. There were no significant differences across all the four sub-groups for sociodemographics. Psychosocial functioning did not differ significantly between PWE with normal psychosocial function and PWE with anxiety alone. However, psychosocial functioning scores were worse in PWE with depression and PWE with both anxiety and depression when compared to PWE with normal psychosocial function.
In the present study of PWE attending an outpatient epilepsy clinic, one-fifth of PWE had both anxiety and depression. Psychosocial functioning in PWE with anxiety was similar to otherwise healthy/normal PWE, whereas PWE with depression showed poor psychosocial functioning. Role of psychological interventions on psychosocial aspects of epilepsy should be studied extensively in future.
心理障碍对癫痫患者（PWE）社会功能的影响尚未得到广泛报道。我们评估了在门诊就诊的PWE的心理社会功能，旨在了解PWE中焦虑、抑郁以及焦虑和抑郁并存情况之间心理社会功能的差异。
使用自我报告的华盛顿心理社会癫痫量表，对连续324名在门诊癫痫诊所就诊的成年PWE的心理社会功能进行前瞻性评估。研究人群分为四组——无心理障碍、焦虑、抑郁以及焦虑和抑郁并存。
研究人群的平均年龄为25.90±6.22岁。73人（22.5%）存在焦虑，60人（18.5%）存在抑郁，70人（21.6%）同时存在焦虑和抑郁，其余心理社会功能正常。四个亚组在社会人口统计学方面无显著差异。心理社会功能正常的PWE与仅患有焦虑的PWE之间无显著差异。然而，与心理社会功能正常的PWE相比，患有抑郁的PWE和同时患有焦虑和抑郁的PWE的心理社会功能得分更差。
在本项针对门诊癫痫诊所PWE的研究中，五分之一的PWE同时患有焦虑和抑郁。患有焦虑的PWE的心理社会功能与其他健康/正常的PWE相似，而患有抑郁的PWE的心理社会功能较差。未来应广泛研究心理干预对癫痫心理社会方面的作用。
