Jiang Hong-Ying, Li Rui-He, Cao Ying, Bai Yi-Hua, Lv Gao-Jie, He Lin, Zhao Ling
Department of Nephrology, the Second Affiliated Hospital of Kunming Medical University, Kunming, China.
Department of Neonatology, the Second Affiliated Hospital of Kunming Medical University, Kunming, China.
Transl Pediatr. 2023 Feb 28;12(2):287-291. doi: 10.21037/tp-22-238. Epub 2023 Feb 16.
The mortality rate of acute kidney injury (AKI) in low-birth-weight premature infants with acute renal failure is extremely high. Since small hemodialysis catheters do not exist, peritoneal dialysis (PD) is the most suitable dialysis method. At present, only a few studies have reported cases of PD in low-birth-weight newborns.
On September 8, 2021, a 10-day-old, low-birth-weight preterm infant, who presented with neonatal respiratory distress syndrome and acute renal failure, was admitted to the Second Affiliated Hospital of Kunming Medical University, China. The patient was the elder of twins and had experienced acute renal failure, hyperkalemia, and anuria following the onset of respiratory distress syndrome. During the initial PD catheterization operation, a double Tenckhoff adult PD catheter cut short by 2 cm was used, with the inner cuff placed in the skin. However, the surgical incision was relatively large, and PD fluid leakage occurred. Later, the incision tore, and the intestines prolapsed when the patient cried. The intestines were returned to the abdominal cavity in an emergency operation, and the PD catheter was placed again. This time, the inner Tenckhoff cuff was placed outside the skin, and PD fluid leakage did not reoccur. However, the patient also experienced a decrease in heart rate and blood pressure, as well as severe pneumonia and peritonitis. Following an active rescue, the patient recovered well.
The PD method effectively treats low-birth-weight preterm neonates with AKI. An adult Tenckhoff catheter was shortened by 2 cm and successfully used in the PD treatment of a low-birth-weight preterm infant. However, the catheter placement should be outside the skin, and the incision should be as small as possible to avoid leakage and incision tears.
急性肾衰竭的低出生体重早产儿急性肾损伤(AKI)死亡率极高。由于不存在小型血液透析导管,腹膜透析(PD)是最合适的透析方法。目前,仅有少数研究报道了低出生体重新生儿的PD病例。
2021年9月8日,一名10日龄、低出生体重的早产儿因新生儿呼吸窘迫综合征和急性肾衰竭入住中国昆明医科大学第二附属医院。该患者为双胞胎中的老大,在呼吸窘迫综合征发病后出现急性肾衰竭、高钾血症和无尿。在初次PD置管手术中,使用了一根缩短2 cm的成人双Tenckhoff PD导管,内套囊置于皮肤内。然而,手术切口相对较大,出现了PD液渗漏。后来,切口撕裂,患者哭闹时肠管脱垂。在急诊手术中将肠管回纳腹腔,并再次放置PD导管。此次,将Tenckhoff内套囊置于皮肤外,未再发生PD液渗漏。然而,患者还出现了心率和血压下降,以及严重的肺炎和腹膜炎。经过积极抢救,患者恢复良好。
PD方法有效治疗低出生体重早产儿的AKI。将一根成人Tenckhoff导管缩短2 cm并成功用于一名低出生体重早产儿的PD治疗。然而,导管放置应在皮肤外,且切口应尽可能小,以避免渗漏和切口撕裂。