Suppr超能文献

星尘模式作为儿童期色素性斯皮茨痣的演变

Stardust Pattern as Evolution of Pigmented Spitz Nevi During Childhood.

作者信息

Brunetti Bruno, Briatico Giulia, Scharf Camila, Cabo Horacio, Scalvenzi Massimiliano, Barbato Filomena, Savoia Francesco, Thomas Luc, Argenziano Giuseppe, Brancaccio Gabriella

机构信息

Ospedale Santa Maria della Speranza, Battipaglia, Italy.

Dermatology Unit, University of Campania, Naples, Italy.

出版信息

Dermatol Pract Concept. 2023 Jan 1;13(1):e2023041. doi: 10.5826/dpc.1301a41.

Abstract

INTRODUCTION

Spitz nevi (SN) are benign melanocytic proliferations frequently occurring in children. Some pigmented SN with a starburst pattern evolve into the "stardust" one, which is characterized by a central, black to gray, hyperpigmented area and remnants of a brown network at the periphery. These dermoscopy changes are often the first alert to induce excision.

OBJECTIVES

The aim of this study is to enlarge the case series of stardust SN in children, in order to increase confidence with this new dermoscopic pattern and reduce unnecessary excisions.

METHODS

This retrospective observational study was conducted with SN cases received from IDS members. The inclusion criteria were: clinical and/or histopathologic diagnosis of Spitz naevus with starburst appearance in children <12 years old, availability of a dermoscopic image at baseline and after follow-up of at least 1 year, availability of patient data. The dermoscopic images and their changes over time were assessed by three evaluators in consensus.

RESULTS

38 SN were enrolled, with a median age of 7 years and a median FUP duration of 15,5 months. Comparing the evolution with time of FUP, no significant differences were found between growing and involuting lesions in terms of patient age and sex, location and palpability of lesions.

CONCLUSIONS

The long follow-up reported in our study could really support the concept of benignity of changing SN. A conservative approach is acceptable for nevi showing the stardust pattern, because it may be considered a physiological evolution of pigmented Spitz nevus, and urgent surgeries could be avoided.

摘要

引言

Spitz痣(SN)是儿童常见的良性黑素细胞增生性病变。一些具有星芒状图案的色素性SN会演变成“星尘”样,其特征为中央有黑色至灰色的色素沉着区,周边有棕色网状残留。这些皮肤镜改变往往是促使切除的首个警示信号。

目的

本研究旨在扩大儿童星尘样SN的病例系列,以增强对这种新皮肤镜模式的信心并减少不必要的切除。

方法

本回顾性观察性研究纳入了从国际皮肤镜学会(IDS)成员处接收的SN病例。纳入标准为:临床和/或组织病理学诊断为12岁以下儿童的星芒状外观Spitz痣,基线时及至少随访1年后有皮肤镜图像,有患者数据。三名评估者共同评估皮肤镜图像及其随时间的变化。

结果

共纳入38例SN,中位年龄为7岁,中位随访时间为15.5个月。比较随访期间病变的演变情况,在患者年龄和性别、病变部位及可触及性方面,生长性病变和消退性病变之间未发现显著差异。

结论

我们研究中报告的长期随访结果确实支持了变化性SN为良性的概念。对于呈现星尘样模式的痣,采用保守方法是可以接受的,因为这可能被视为色素性Spitz痣的一种生理性演变,可避免紧急手术。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5580/9946083/13040ca9297e/2547dp1301a41g001.jpg

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验