• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

相似文献

1
Infections in Hospitalized Patients with Psoriasis in a Skin Referral Hospital.一家皮肤专科医院中住院银屑病患者的感染情况
Dermatol Pract Concept. 2023 Jan 1;13(1):e2023027. doi: 10.5826/dpc.1301a27.
2
Risk of Serious Infection With Biologic and Systemic Treatment of Psoriasis: Results From the Psoriasis Longitudinal Assessment and Registry (PSOLAR).银屑病的生物制剂和系统治疗的严重感染风险：来自银屑病纵向评估和登记研究（PSOLAR）的结果。
JAMA Dermatol. 2015 Sep;151(9):961-9. doi: 10.1001/jamadermatol.2015.0718.
3
Infliximab for severe, treatment-resistant psoriasis: a prospective, open-label study.英夫利昔单抗治疗重度、难治性银屑病：一项前瞻性、开放标签研究。
Br J Dermatol. 2006 Jul;155(1):160-9. doi: 10.1111/j.1365-2133.2006.07316.x.
4
Biologic Therapy Utilization in Patients With Moderate to Severe Psoriasis and Psoriatic Arthritis: An Observational Summary of Biologic Therapy Use in a Clinical Setting.中重度银屑病和银屑病关节炎患者的生物治疗应用：临床环境中生物治疗使用情况的观察总结
J Cutan Med Surg. 2018 Nov/Dec;22(6):567-576. doi: 10.1177/1203475418786712. Epub 2018 Jun 28.
5
Safety profiles and efficacy of infliximab therapy in Japanese patients with plaque psoriasis with or without psoriatic arthritis, pustular psoriasis or psoriatic erythroderma: Results from the prospective post-marketing surveillance.英夫利昔单抗治疗日本斑块状银屑病患者（伴或不伴银屑病关节炎、脓疱型银屑病或红皮病型银屑病）的安全性和疗效：上市后前瞻性监测结果
J Dermatol. 2016 Jul;43(7):767-78. doi: 10.1111/1346-8138.13214. Epub 2015 Dec 24.
6
Biologic drug survival in Israeli psoriasis patients.以色列银屑病患者的生物药物存活情况。
J Am Acad Dermatol. 2017 Apr;76(4):662-669.e1. doi: 10.1016/j.jaad.2016.10.033. Epub 2016 Dec 28.
7
Infliximab is associated with an increased risk of serious infection in patients with psoriasis in the U.K. and Republic of Ireland: results from the British Association of Dermatologists Biologic Interventions Register (BADBIR).英夫利昔单抗与英国和爱尔兰银屑病患者严重感染风险增加相关：英国皮肤科医师协会生物干预注册处（BADBIR）的结果。
Br J Dermatol. 2019 Feb;180(2):329-337. doi: 10.1111/bjd.17036. Epub 2018 Oct 21.
8
Clinical profile, morbidity, and outcome of adult-onset generalized pustular psoriasis: analysis of 102 cases seen in a tertiary hospital in Johor, Malaysia.成人泛发性脓疱型银屑病的临床特征、发病率及转归：马来西亚柔佛州一家三级医院102例病例分析
Int J Dermatol. 2014 Jun;53(6):676-84. doi: 10.1111/ijd.12070. Epub 2013 Aug 22.
9
Interventions for nail psoriasis.指甲银屑病的干预措施。
Cochrane Database Syst Rev. 2013 Jan 31;2013(1):CD007633. doi: 10.1002/14651858.CD007633.pub2.
10
Risk of Serious Infection in Patients Receiving Systemic Medications for the Treatment of Psoriasis.接受全身性药物治疗银屑病的患者发生严重感染的风险
JAMA Dermatol. 2019 Oct 1;155(10):1142-1152. doi: 10.1001/jamadermatol.2019.1121.

引用本文的文献

1
Prevalence of fungal colonization among patients with psoriasis in difficult-to-treat areas: impact of apremilast on mycotic burden and clinical outcomes.银屑病患者在难治疗部位的真菌定植患病率：阿普米拉斯对真菌负荷和临床结局的影响。
Front Immunol. 2024 Dec 10;15:1508489. doi: 10.3389/fimmu.2024.1508489. eCollection 2024.

本文引用的文献

1
Oral simvastatin combined with narrowband UVB for the treatment of psoriasis: A randomized controlled trial.口服辛伐他汀联合窄谱 UVB 治疗银屑病：一项随机对照试验。
Dermatol Ther. 2021 Sep;34(5):e15075. doi: 10.1111/dth.15075. Epub 2021 Aug 19.
2
The utility of systemic-immune inflammation index for predicting the disease activation in patients with psoriasis.全身性免疫炎症指数在预测银屑病患者疾病活动中的作用。
Int J Clin Pract. 2021 Jun;75(6):e14101. doi: 10.1111/ijcp.14101. Epub 2021 Mar 6.
3
A cutoff value for the Systemic Immune-Inflammation Index in determining activity of Behçet disease.用于确定 Behcet 病活动的全身性免疫炎症指数的截断值。
Clin Exp Dermatol. 2021 Mar;46(2):286-291. doi: 10.1111/ced.14432. Epub 2020 Oct 10.
4
National, regional, and worldwide epidemiology of psoriasis: systematic analysis and modelling study.银屑病的国家、地区和全球流行病学：系统分析和建模研究。
BMJ. 2020 May 28;369:m1590. doi: 10.1136/bmj.m1590.
5
Psoriasis Pathogenesis and Treatment.银屑病发病机制与治疗。
Int J Mol Sci. 2019 Mar 23;20(6):1475. doi: 10.3390/ijms20061475.
6
Infliximab is associated with an increased risk of serious infection in patients with psoriasis in the U.K. and Republic of Ireland: results from the British Association of Dermatologists Biologic Interventions Register (BADBIR).英夫利昔单抗与英国和爱尔兰银屑病患者严重感染风险增加相关：英国皮肤科医师协会生物干预注册处（BADBIR）的结果。
Br J Dermatol. 2019 Feb;180(2):329-337. doi: 10.1111/bjd.17036. Epub 2018 Oct 21.
7
Prevalence and Possible Role of Species in Patients with Psoriasis: A Systematic Review and Meta-Analysis.银屑病患者中 种的流行情况及其可能作用：系统评价和荟萃分析。
Mediators Inflamm. 2018 May 6;2018:9602362. doi: 10.1155/2018/9602362. eCollection 2018.
8
Oral Candida colonization and plaque type psoriasis: Is there any relationship?口腔念珠菌定植与斑块型银屑病：存在关联吗？
J Investig Clin Dent. 2018 Aug;9(3):e12335. doi: 10.1111/jicd.12335. Epub 2018 Mar 30.
9
Risk of Serious Infection, Opportunistic Infection, and Herpes Zoster among Patients with Psoriasis in the United Kingdom.英国银屑病患者的严重感染、机会性感染和带状疱疹风险。
J Invest Dermatol. 2018 Aug;138(8):1726-1735. doi: 10.1016/j.jid.2018.01.039. Epub 2018 Mar 2.
10
Risk of Serious Infection in Patients with Psoriasis Receiving Biologic Therapies: A Prospective Cohort Study from the British Association of Dermatologists Biologic Interventions Register (BADBIR).接受生物疗法治疗的银屑病患者发生严重感染的风险：来自英国皮肤科医生生物干预注册处（BADBIR）的前瞻性队列研究。
J Invest Dermatol. 2018 Mar;138(3):534-541. doi: 10.1016/j.jid.2017.10.005. Epub 2017 Oct 17.

一家皮肤专科医院中住院银屑病患者的感染情况

Infections in Hospitalized Patients with Psoriasis in a Skin Referral Hospital.

作者信息

Zaredar Nafise, Mahmoudi Hamidreza, Soori Tahereh, Teimourpour Amir, Balighi Kamran, Farid Ali Salehi, Daneshpazhooh Maryam

机构信息

Department of Dermatology, Tehran University of Medical Sciences, Tehran, Iran.

Autoimmune Bullous Diseases Research Center, Tehran University of Medical Sciences, Tehran, Iran.

出版信息

Dermatol Pract Concept. 2023 Jan 1;13(1):e2023027. doi: 10.5826/dpc.1301a27.

DOI:10.5826/dpc.1301a27
PMID:36892397
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9946094/
Abstract

INTRODUCTION

Psoriasis and its treatments may predispose patients to various infections. This is considered one of the most significant complications in patients with psoriasis.

OBJECTIVES

In the present study, we aimed to determine the prevalence of infection in hospitalized psoriasis patients and its relationship with systemic and biologic treatments.

METHODS

All hospitalized patients with psoriasis from 2018 to 2020 in Razi Hospital in Tehran, Iran, were studied and cases of infection were recorded.

RESULTS

Overall, 516 patients were studied and 25 types of infection in 111 patients were found. The most common types of infection were pharyngitis and cellulitis, followed by oral candida, urinary tract infections, common cold, fever of unknown origin, and pneumonia. Female sex and pustular psoriasis were significantly associated with infection in psoriatic patients. Those patients who received prednisolone had a higher risk of infection, and those under treatment with methotrexate or infliximab had a lower risk of infection.

CONCLUSION

Overall, 21.5% of psoriasis patients in our study had at least one episode of infection. This demonstrates that the prevalence of infection in these patients is not low. Using systemic steroids was associated with a higher risk of infection, while using methotrexate or infliximab was concomitant with a lower risk of infection.

摘要

引言

银屑病及其治疗可能使患者易患各种感染。这被认为是银屑病患者最重要的并发症之一。

目的

在本研究中，我们旨在确定住院银屑病患者的感染发生率及其与全身治疗和生物治疗的关系。

方法

对2018年至2020年在伊朗德黑兰拉齐医院住院的所有银屑病患者进行研究，并记录感染病例。

结果

总体而言，共研究了516例患者，发现111例患者发生了25种类型的感染。最常见的感染类型是咽炎和蜂窝织炎，其次是口腔念珠菌感染、尿路感染、普通感冒、不明原因发热和肺炎。女性和脓疱型银屑病与银屑病患者的感染显著相关。接受泼尼松龙治疗的患者感染风险较高，而接受甲氨蝶呤或英夫利昔单抗治疗的患者感染风险较低。

结论

总体而言，我们研究中的银屑病患者中有21.5%至少发生过一次感染。这表明这些患者的感染发生率并不低。使用全身类固醇与较高的感染风险相关，而使用甲氨蝶呤或英夫利昔单抗则与较低的感染风险相关。