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呼吁“关注骨骼”:骨质疏松是全髋关节和膝关节置换术后两年不良结局的预测因素。

A call to "own the bone": osteoporosis is a predictor for adverse two-year outcomes following total hip and knee arthroplasty.

机构信息

Department of Orthopaedic Surgery and Rehabilitation Medicine, The State University of New York Downstate Health Sciences University, 450 Clarkson Ave, MSC 30, Brooklyn, NY, 11203, USA.

Department of Orthopaedic Surgery, Warren Alpert School of Medicine, Brown University, Providence, RI, USA.

出版信息

Eur J Orthop Surg Traumatol. 2023 Oct;33(7):2889-2894. doi: 10.1007/s00590-023-03499-w. Epub 2023 Mar 9.

Abstract

PURPOSE

While bone health is instrumental in orthopedic surgery, few studies have described the long-term outcomes of osteoporosis (OP) in patients undergoing total hip (THA) or knee (TKA) arthroplasties.

METHODS

Using the New York State statewide planning and research cooperative system database, all patients who underwent primary TKA or THA for osteoarthritis from 2009 to 2011 with minimum 2-year follow-up were identified. They were divided based on their OP status (OP and non-OP) and 1:1 propensity score matched for age, sex, race, and Charlson/Deyo index. Cohorts were compared for demographics, hospital-related parameters, and 2-year postoperative complications and reoperations. Multivariate binary logistic regression was utilized to identify significant independent associations with 2-year medical and surgical complications and revisions.

RESULTS

A total of 11,288 TKA and 8248 THA patients were identified. OP and non-OP TKA patients incurred comparable overall hospital charges for their surgical visit and hospital length of stay (LOS) (both, p ≥ 0.125). Though OP and non-OP THA patients incurred similar mean hospital charges for their surgical visit, they experienced longer hospital LOS (4.3 vs. 4.1 days, p = 0.035). For both TKA and THA, OP patients had higher rates of overall and individual medical and surgical complications (all, p < 0.05). OP was independently associated with the 2-year occurrence of any overall, surgical, and medical complications, and any revision in TKA and THA patients (all, OR ≥ 1.42, p < 0.001).

CONCLUSION

Our study found OP was associated with a greater risk of 2-year adverse outcomes following TKA or THA, including medical, surgical, and overall complications as well as revision operations compared to non-OP patients.

摘要

目的

骨骼健康是骨科手术的关键,但很少有研究描述过骨质疏松症(OP)患者行全髋关节置换术(THA)或全膝关节置换术(TKA)后的长期结果。

方法

利用纽约州全州规划和研究合作系统数据库,确定了 2009 年至 2011 年期间因骨关节炎行初次 TKA 或 THA 且随访时间至少 2 年的所有患者。根据 OP 状态(OP 和非 OP)将其分为两组,并按年龄、性别、种族和 Charlson/Deyo 指数进行 1:1 倾向评分匹配。比较两组患者的人口统计学、医院相关参数以及术后 2 年的并发症和再次手术情况。采用多变量二项逻辑回归分析确定与术后 2 年医疗和手术并发症及翻修相关的显著独立关联因素。

结果

共确定了 11288 例 TKA 和 8248 例 THA 患者。OP 和非 OP TKA 患者的手术就诊和住院总费用相当(均,p≥0.125)。尽管 OP 和非 OP THA 患者的手术就诊平均住院费用相似,但他们的住院时间更长(4.3 天比 4.1 天,p=0.035)。对于 TKA 和 THA,OP 患者的总体和各种医疗和手术并发症发生率均较高(均,p<0.05)。OP 与 TKA 和 THA 患者术后 2 年内发生的任何总体、手术和医疗并发症以及任何翻修手术独立相关(OR≥1.42,均,p<0.001)。

结论

本研究发现,与非 OP 患者相比,OP 患者在 TKA 或 THA 后 2 年内发生不良结局的风险更高,包括医疗、手术和总体并发症以及翻修手术。

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