South Tees Hospitals NHS Foundation Trust, Middlesbrough, UK.
The Mary Kinross Trust and RCS Chair, Department of Health Sciences and Hull York Medical School, University of York, York, UK.
Rheumatol Int. 2023 Jun;43(6):985-1014. doi: 10.1007/s00296-023-05298-2. Epub 2023 Mar 10.
Joint hypermobility affects approximately 30% of the United Kingdom (UK) population, characterised by the ability to move joints beyond the physiological limits. Associated conditions include Ehlers-Danlos syndrome and hypermobility spectrum disorders, affecting individuals across physical, psychological and social levels detrimentally impacting their health and wellbeing. The scoping review aims to describe the known biopsychosocial impact of joint hypermobility conditions in adults over the last decade. Additional objectives include to (1) identify the types of studies that address these factors, (2) to understand how the impact of the condition is measured and managed and (3) what healthcare professionals (HCPs) are involved. The scoping review was conducted using the five-stage framework by Arksey and O'Malley. The search strategy related to two main keywords, "hypermobility" and, "biopsychosocial" across a number of electronic databases. A pilot search was conducted to determine the suitability of the databases and terms. Following the search, the data was extracted and charted, summarised and narratively reported. 32 studies met the inclusion criteria. The majority were conducted in either the UK or United States of America and case-control in design. The biopsychosocial impact was wide-ranging including, but not limited to, musculoskeletal system and dermatology, gastroenterology, mood and anxiety disorders, education and employments. This review is the first of its kind to summarise all reported symptoms and impact of joint hypermobility conditions in adults, highlighting a clear need to promote a multidisciplinary and holistic approach in raising awareness of these conditions and improving their management.
关节过度活动症影响了英国约 30%的人口，其特征是关节活动超出生理极限。相关疾病包括埃勒斯-当洛斯综合征和过度活动综合征，影响到身体、心理和社会各个层面的个体，对他们的健康和幸福感造成负面影响。本范围综述旨在描述过去十年中成人关节过度活动症的已知生物心理社会影响。其他目标包括：(1) 确定解决这些因素的研究类型；(2) 了解如何衡量和管理疾病的影响；(3) 涉及哪些医疗保健专业人员。本范围综述使用 Arksey 和 O'Malley 的五阶段框架进行。搜索策略涉及两个主要关键词，即“过度活动”和“生物心理社会”，在多个电子数据库中进行搜索。进行了一次试点搜索，以确定数据库和术语的适用性。搜索完成后，提取和图表化数据，进行总结和叙述性报告。有 32 项研究符合纳入标准。这些研究大多数是在英国或美国进行的，设计为病例对照。生物心理社会影响范围广泛，包括但不限于肌肉骨骼系统和皮肤病、胃肠道、情绪和焦虑障碍、教育和就业。这是同类综述中第一次总结成人关节过度活动症的所有报告症状和影响，明确需要促进多学科和整体方法，提高对这些疾病的认识并改善其管理。
