Yam Jason C S, Kwok Alvin K H
Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, 4/F, Hong Kong Eye Hospital, 147 K Argyle Street, Kowloon, Hong Kong, People's Republic of China,
Int Ophthalmol. 2014 Apr;34(2):383-400. doi: 10.1007/s10792-013-9791-x. Epub 2013 May 31.
The objective of this study is to review the association between ultraviolet (UV) light and ocular diseases. The data are sourced from the literature search of Medline up to Nov 2012, and the extracted data from original articles, review papers, and book chapters were reviewed. There is a strong evidence that ultraviolet radiation (UVR) exposure is associated with the formation of eyelid malignancies [basal cell carcinoma (BCC) and squamous cell carcinoma (SCC)], photokeratitis, climatic droplet keratopathy (CDK), pterygium, and cortical cataract. However, the evidence of the association between UV exposure and development of pinguecula, nuclear and posterior subcapsular cataract, ocular surface squamous neoplasia (OSSN), and ocular melanoma remained limited. There is insufficient evidence to determine whether age-related macular degeneration (AMD) is related to UV exposure. It is now suggested that AMD is probably related to visible radiation especially blue light, rather than UV exposure. From the results, it was concluded that eyelid malignancies (BCC and SCC), photokeratitis, CDK, pterygium, and cortical cataract are strongly associated with UVR exposure. Evidence of the association between UV exposure and development of pinguecula, nuclear and posterior subcapsular cataract, OSSN, and ocular melanoma remained limited. There is insufficient evidence to determine whether AMD is related to UV exposure. Simple behaviural changes, appropriate clothing, wearing hats, and UV blocking spectacles, sunglasses or contact lens are effective measures for UV protection.
本研究的目的是回顾紫外线（UV）与眼部疾病之间的关联。数据来源于截至2012年11月对Medline的文献检索，并对从原始文章、综述论文和书籍章节中提取的数据进行了审查。有强有力的证据表明，紫外线辐射（UVR）暴露与眼睑恶性肿瘤[基底细胞癌（BCC）和鳞状细胞癌（SCC）]、光性角膜炎、气候性小滴状角膜病变（CDK）、翼状胬肉和皮质性白内障的形成有关。然而，紫外线暴露与睑裂斑、核性和后囊下白内障、眼表鳞状上皮肿瘤（OSSN）以及眼黑色素瘤发生之间关联的证据仍然有限。没有足够的证据来确定年龄相关性黄斑变性（AMD）是否与紫外线暴露有关。现在认为，AMD可能与可见光尤其是蓝光有关，而不是与紫外线暴露有关。从结果得出结论，眼睑恶性肿瘤（BCC和SCC）、光性角膜炎、CDK、翼状胬肉和皮质性白内障与UVR暴露密切相关。紫外线暴露与睑裂斑、核性和后囊下白内障、OSSN以及眼黑色素瘤发生之间关联的证据仍然有限。没有足够的证据来确定AMD是否与紫外线暴露有关。简单的行为改变、穿着合适的衣物、戴帽子以及佩戴防紫外线眼镜、太阳镜或隐形眼镜是有效的紫外线防护措施。
