Zhang Dongxin, Chen Lvjia, Deng Huiqing, Zhang Ying, Cheng Qihang, Zhang Qian-Feng
Institute of Molecular Engineering and Applied Chemistry, Anhui University of Technology No. 59 Hudong Road Ma'anshan 243002 China
RSC Adv. 2023 Mar 7;13(11):7432-7435. doi: 10.1039/d2ra08257h. eCollection 2023 Mar 1.
Asymmetric ring-opening reactions of donor-acceptor cyclopropanes with 1,3-cyclodiones have been established for the synthesis of enantioenriched γ-hydroxybutyric acid derivatives in the presence of Cu(ii)/trisoxazoline catalyst. These reactions offered the desired products in 70% to 93% yields with 79% to 99% enantiomeric excesses.
在铜（II）/三恶唑啉催化剂存在下，已实现给体-受体环丙烷与1,3-环二酮的不对称开环反应，用于合成对映体富集的γ-羟基丁酸衍生物。这些反应以70%至93%的产率和79%至99%的对映体过量提供所需产物。
