Clinical Prevention Research, Steno Diabetes Center Copenhagen, Herlev, Denmark.
Department of Biomedical Sciences, University of Copenhagen, Copenhagen, Denmark.
Diabetologia. 2023 Jun;66(6):1016-1023. doi: 10.1007/s00125-023-05890-y. Epub 2023 Mar 10.
The current definition of prediabetes is controversial and subject to continuous debate. Nonetheless, prediabetes is a risk factor for type 2 diabetes, is highly prevalent and is associated with diabetic complications and mortality. Thereby, it has the potential to become a huge strain on healthcare systems in the future, necessitating action from legislators and healthcare providers. But how do we best reduce its associated burden on health? As a compromise between differing opinions in the literature and among the authors of this article, we suggest stratifying individuals with prediabetes according to estimated risk and only offering individual-level preventive interventions to those at high risk. At the same time, we argue to identify those with prediabetes and already established diabetes-related complications and treat them as we would treat individuals with established type 2 diabetes.
目前对糖尿病前期的定义存在争议，且仍在不断讨论中。然而，糖尿病前期是 2 型糖尿病的一个风险因素，其具有较高的发病率，并与糖尿病并发症和死亡率相关。因此，它有可能成为未来医疗体系的巨大负担，需要立法者和医疗服务提供者采取行动。但是，我们如何才能最好地减轻其对健康的相关负担呢？在文献和本文作者的不同意见之间做出妥协，我们建议根据估计的风险对糖尿病前期患者进行分层，仅对高风险患者进行个体化预防干预。同时，我们主张识别出已经患有糖尿病前期和相关并发症的患者，并按照治疗已确诊 2 型糖尿病患者的方式对其进行治疗。
