医用大麻治疗慢性非恶性疼痛管理。
Medical Cannabis for Chronic Nonmalignant Pain Management.
机构信息
Larkin Community Hospital, South Miami, FL, USA.
Department of Osteopathic Neuromuscular Medicine/Neurology, Canna MD & Larkin Community Hospital, Miami, FL, USA.
出版信息
Curr Pain Headache Rep. 2023 Apr;27(4):57-63. doi: 10.1007/s11916-023-01101-w. Epub 2023 Mar 10.
PURPOSE OF REVIEW
Cannabis has been used since ancient times for medical and recreational research. This review article will document the validity of how medical cannabis can be utilized for chronic nonmalignant pain management.
RECENT FINDINGS
Current cannabis research has shown that medical cannabis is indicated for symptom management for many conditions not limited to cancer, chronic pain, headaches, migraines, and psychological disorders (anxiety and post-traumatic stress disorder). Δ9-Tetrahydrocannabinol (THC) and cannabidiol (CBD) are active ingredients in cannabis that modulate a patient's symptoms. These compounds work to decrease nociception and symptom frequency via the endocannabinoid system. Research regarding pain management is limited within the USA as the Drug Enforcement Agency (DEA) classifies it as a schedule one drug. Few studies have found a limited relationship between chronic pain and medical cannabis use. A total of 77 articles were selected after a thorough screening process using PubMed and Google Scholar. This paper demonstrates that medical cannabis use provides adequate pain management. Patients suffering from chronic nonmalignant pain may benefit from medical cannabis due to its convenience and efficacy.
目的综述
大麻自古就被用于医学和娱乐研究。本文将记录医用大麻在慢性非恶性疼痛管理中的有效性。
最近的发现
目前的大麻研究表明，医用大麻可用于治疗多种疾病的症状，不仅限于癌症、慢性疼痛、头痛、偏头痛和心理障碍（焦虑和创伤后应激障碍）。Δ9-四氢大麻酚（THC）和大麻二酚（CBD）是大麻中的活性成分，可调节患者的症状。这些化合物通过内源性大麻素系统来减少伤害感受和症状频率。由于美国毒品管制局（DEA）将其归类为附表 I 药物，美国对疼痛管理的研究受到限制。很少有研究发现慢性疼痛与医用大麻使用之间存在有限的关系。经过对 PubMed 和 Google Scholar 的全面筛选，共选择了 77 篇文章。本文表明，医用大麻的使用可以提供充分的疼痛管理。由于医用大麻的便利性和疗效，患有慢性非恶性疼痛的患者可能会从中受益。
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