Department of Rehabilitation, Graduate School of Health Science, Saitama Prefectural University, Koshigaya, Saitama, Japan.
Medicine (Baltimore). 2023 Mar 10;102(10):e33222. doi: 10.1097/MD.0000000000033222.
Alcohol use disorder (AUD) may be associated with increased attentional bias (AB) toward alcohol-related information. Accordingly, our aim was to explore the relationships between alcohol-related AB, cravings, and risk of relapse among individuals with AUD after treatment. The study group included 24 in-patients with AUD who had completed alcohol withdrawal management. AB was evaluated using an image-based task, with participants asked to select the nonalcoholic image as fast and as accurately as possible and the response time (RT) measured. The intensity of the desire to drink was evaluated using a 100-mm Visual Analog Scale and the risk of relapse using the Alcohol Relapse Risk Scale. Linear regression was used to evaluate the relationship between these variables, with age, gender, duration of hospitalization, and depression score used as covariates. Intensity of cravings was significantly associated with AB RT (R2 =.625) and risk of relapse of drinking behavior (Alcohol Relapse Risk Scale score, R2 =.64). Gender and γ-GTP were significant explanatory variables of identified relationships. The main limitations of our study are a higher proportion of men than women in our study group and the absence of a control group for baseline comparison of AB RTs. This study results suggested that the desire to drink is related to AB among patients with AUD and that the intensity of the desire to drink is related to the risk of a relapse in drinking behavior after AUD treatment.
酒精使用障碍（AUD）可能与对酒精相关信息的注意力偏差（AB）增加有关。因此，我们的目的是探讨治疗后 AUD 个体的酒精相关 AB、渴望和复发风险之间的关系。研究组包括 24 名完成酒精戒断管理的 AUD 住院患者。使用基于图像的任务评估 AB，要求参与者尽可能快速和准确地选择非酒精图像，并测量反应时间（RT）。使用 100 毫米视觉模拟量表评估饮酒欲望的强度，使用酒精复发风险量表评估复发风险。使用线性回归评估这些变量之间的关系，将年龄、性别、住院时间和抑郁评分作为协变量。渴望的强度与 AB RT（R2=.625）和饮酒行为复发风险（酒精复发风险量表评分，R2=.64）显著相关。性别和γ-GTP 是确定关系的重要解释变量。本研究的主要局限性是研究组中男性比例高于女性，以及缺乏对照组来比较 AB RT 的基线。本研究结果表明，渴望饮酒与 AUD 患者的 AB 有关，渴望的强度与 AUD 治疗后饮酒行为复发的风险有关。
