Martins Gonçalves Thayna, Mitsue Saruhashi Shimabukuro Patrícia, Nakamura Hiraki Karen Renata, Braz-Silva Paulo Henrique, Giannecchini Simone, Kai-Wang To Kelvin, Taminato Monica, Borges de Morais Richarlisson
Medical School, Federal University of Uberlandia, Uberlandia, Brazil.
Paulista Nursing School, Federal University of São Paulo, São Paulo, Brazil.
J Infect Dev Ctries. 2023 Feb 28;17(2):241-250. doi: 10.3855/jidc.16801.
Influenza is characterized by an acute viral infection, which can lead to severe conditions and death, especially in vulnerable populations, such as older adults. Therefore, we sought to analyze cases of severe acute respiratory syndrome (SARS) due to influenza in older adults registered in Brazil and investigate the factors related to death due to this disease.
This is a cross-sectional, population-based study that used secondary data from the Influenza Epidemiological Surveillance Information System (IESIS-Influenza). Older adults aged 60 years and above with laboratory diagnosis of influenza were included.
A total of 3,547 older adults with SARS due to influenza were included, out of which 1,185 cases with death as the outcome were identified. Among older adults with death as the outcome, 87.4% were not vaccinated against influenza. The main risk factors for death were invasive ventilatory support use, intensive care unit admission, brown skin color and dyspnea (p < 0.001).
This study described the profile of older adults with SARS due to influenza in Brazil. Factors associated with death in this population were identified. Moreover, the need to encourage compliance with vaccination among older adults is evident in order to prevent severe cases and unfavorable outcomes related to influenza.
流感的特点是急性病毒感染，可导致严重病症甚至死亡，尤其是在老年人等弱势群体中。因此，我们试图分析巴西登记的老年人因流感导致的严重急性呼吸综合征（SARS）病例，并调查与该疾病死亡相关的因素。
这是一项基于人群的横断面研究，使用了来自流感流行病学监测信息系统（IESIS-流感）的二手数据。纳入了60岁及以上经实验室诊断为流感的老年人。
总共纳入了3547例因流感导致SARS的老年人，其中确定了1185例以死亡为结局的病例。在以死亡为结局的老年人中，87.4%未接种流感疫苗。死亡的主要危险因素是使用有创通气支持、入住重症监护病房、棕色皮肤和呼吸困难（p<0.001）。
本研究描述了巴西因流感导致SARS的老年人的情况。确定了该人群中与死亡相关的因素。此外，为预防与流感相关的严重病例和不良结局，显然有必要鼓励老年人遵守疫苗接种规定。
