2020/2021 年在匈牙利的欧洲獾（Meles meles）中发现的一种新型杯状病毒（杯状病毒科）。

A novel vesivirus (family Caliciviridae) in European badgers (Meles meles) in Hungary, 2020/2021.

机构信息

Department of Medical Microbiology and Immunology Medical School, University of Pécs, Szigeti út 12, H-7624, Pécs, Hungary.

Department of Animal Physiology and Health, Hungarian University of Agriculture and Life Science, Kaposvár Campus, Kaposvár, Hungary.

出版信息

Arch Virol. 2023 Mar 11;168(4):108. doi: 10.1007/s00705-023-05733-6.

DOI:10.1007/s00705-023-05733-6

PMID:36899117

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10006033/

Abstract

In this study, a novel vesivirus (family Caliciviridae) was detected and characterized in faecal and tissue (blood and spleen) specimens collected from three (23.1%) out of 13 European badgers (Meles meles) in Hungary that were tested using RT-PCR and sequencing methods. The complete genome of the vesivirus strain European badger/B40/2021/HUN (OQ161773) is 8,375 nucleotides in length. The ORF1, ORF2, and ORF3 proteins have 81.1%, 70.5%, and 64.2% amino acid sequence identity, respectively, to the corresponding proteins of Asian badger vesivirus, which was first reported in badgers in China in 2022. These results indicate that more than one lineage/species of vesiviruses circulates in mustelid badgers in geographically different regions.

摘要

在这项研究中，使用 RT-PCR 和测序方法检测并分析了来自匈牙利的 13 只欧洲獾（Meles meles）中的 3 只（23.1%）的粪便和组织（血液和脾脏）样本，发现了一种新型杯状病毒（杯状病毒科）。该杯状病毒株欧洲獾/B40/2021/HUN（OQ161773）的完整基因组长 8375 个核苷酸。ORF1、ORF2 和 ORF3 蛋白分别与 2022 年在中国首次在獾中报道的亚洲獾杯状病毒的相应蛋白具有 81.1%、70.5%和 64.2%的氨基酸序列同一性。这些结果表明，在地理上不同的地区，多种杯状病毒/物种在鼬科獾中传播。