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The role of stromal BMP/CXCL12 signaling axis in serrated polyp development.

作者信息

Nagao Munemasa, Fukuda Akihisa

机构信息

Department of Gastroenterology and Hepatology, Kyoto University Graduate School of Medicine, 54 Shogoin-Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan.

Department of Gastroenterology and Hepatology, Tenri Hospital, 200 Mishima-cho, Tenri, Nara, 632-8552, Japan.

出版信息

J Gastroenterol. 2023 Apr;58(4):429-430. doi: 10.1007/s00535-023-01978-9. Epub 2023 Mar 11.

DOI:10.1007/s00535-023-01978-9
PMID:36899173
Abstract
摘要

相似文献

1
The role of stromal BMP/CXCL12 signaling axis in serrated polyp development.基质BMP/CXCL12信号轴在锯齿状息肉发生中的作用。
J Gastroenterol. 2023 Apr;58(4):429-430. doi: 10.1007/s00535-023-01978-9. Epub 2023 Mar 11.
2
Loss of bone morphogenetic protein signaling in fibroblasts results in CXCL12-driven serrated polyp development.成纤维细胞中骨形态发生蛋白信号的丧失导致 CXCL12 驱动的锯齿状息肉的发展。
J Gastroenterol. 2023 Jan;58(1):25-43. doi: 10.1007/s00535-022-01928-x. Epub 2022 Nov 3.
3
Cyclooxygenase-2 overexpression is common in serrated and non-serrated colorectal adenoma, but uncommon in hyperplastic polyp and sessile serrated polyp/adenoma.环氧化酶-2过表达在锯齿状和非锯齿状大肠腺瘤中常见，但在增生性息肉和无蒂锯齿状息肉/腺瘤中不常见。
BMC Cancer. 2008 Jan 29;8:33. doi: 10.1186/1471-2407-8-33.
4
Benign serrated colorectal fibroblastic polyps/intramucosal perineuriomas are true mixed epithelial-stromal polyps (hybrid hyperplastic polyp/mucosal perineurioma) with frequent BRAF mutations.良性锯齿状结直肠纤维性息肉/黏膜下神经鞘瘤是真正的混合上皮-间质息肉（混合性增生性息肉/黏膜下神经鞘瘤），常伴有 BRAF 突变。
Am J Surg Pathol. 2010 Nov;34(11):1663-71. doi: 10.1097/PAS.0b013e3181f4a458.
5
[Serrated, hyperplastic and hyperplasia-like colorectal polyps].[锯齿状、增生性及增生样结直肠息肉]
Ugeskr Laeger. 2006 Nov 13;168(46):4005-9.
6
Variation in the detection of serrated polyps in an average risk colorectal cancer screening cohort.在平均风险结直肠癌筛查队列中锯齿状息肉的检出存在差异。
Am J Gastroenterol. 2010 Dec;105(12):2656-64. doi: 10.1038/ajg.2010.315. Epub 2010 Aug 17.
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Endoscopic characteristics of colorectal serrated lesions.结直肠锯齿状病变的内镜特征。
Hepatogastroenterology. 2011 Jul-Aug;58(109):1163-7. doi: 10.5754/hge10093.
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Serrated epithelial colorectal polyps (hyperplastic polyps, sessile serrated adenomas) with perineurial stroma: Clinicopathological and molecular analysis of a new series.具有神经束膜间质的锯齿状结直肠上皮息肉（增生性息肉、无蒂锯齿状腺瘤）：一组新病例的临床病理及分子分析
Ann Diagn Pathol. 2018 Aug;35:48-52. doi: 10.1016/j.anndiagpath.2018.05.002. Epub 2018 May 4.
9
Impact of an Endoscopic Quality Improvement Program Focused on Adenoma Detection on Sessile Serrated Adenoma/Polyp Detection.一项聚焦腺瘤检测的内镜质量改进计划对无蒂锯齿状腺瘤/息肉检测的影响。
Dig Dis Sci. 2017 Jun;62(6):1464-1471. doi: 10.1007/s10620-017-4582-2. Epub 2017 Apr 25.
10
BRAF and KRAS Mutations in hyperplastic polyps and serrated adenomas of the colorectum: relationship to histology and CpG island methylation status.结直肠增生性息肉和锯齿状腺瘤中的BRAF和KRAS突变：与组织学及CpG岛甲基化状态的关系
Am J Surg Pathol. 2004 Nov;28(11):1452-9. doi: 10.1097/01.pas.0000141404.56839.6a.

本文引用的文献

1
Loss of bone morphogenetic protein signaling in fibroblasts results in CXCL12-driven serrated polyp development.成纤维细胞中骨形态发生蛋白信号的丧失导致 CXCL12 驱动的锯齿状息肉的发展。
J Gastroenterol. 2023 Jan;58(1):25-43. doi: 10.1007/s00535-022-01928-x. Epub 2022 Nov 3.
2
Clinicopathological characteristics of colorectal serrated polyposis syndrome (SPS): results of a multicenter study by the SPS Study Group in Japan.结直肠锯齿状息肉病综合征（SPS）的临床病理特征：日本SPS研究组的多中心研究结果
J Gastroenterol. 2022 Apr;57(4):300-308. doi: 10.1007/s00535-022-01859-7. Epub 2022 Feb 24.
3
Colorectal carcinoma occurring via the adenoma-carcinoma pathway in patients with serrated polyposis syndrome.
锯齿状息肉病综合征患者通过腺瘤-癌途径发生的结直肠癌。
J Gastroenterol. 2022 Apr;57(4):286-299. doi: 10.1007/s00535-022-01858-8. Epub 2022 Feb 23.
4
Targeting the immune milieu in gastrointestinal cancers.针对胃肠道癌症的免疫微环境。
J Gastroenterol. 2020 Oct;55(10):909-926. doi: 10.1007/s00535-020-01710-x. Epub 2020 Aug 3.
5
Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries.全球癌症统计数据 2018：GLOBOCAN 对全球 185 个国家/地区 36 种癌症的发病率和死亡率的估计。
CA Cancer J Clin. 2018 Nov;68(6):394-424. doi: 10.3322/caac.21492. Epub 2018 Sep 12.
6
The molecular characteristics of colorectal cancer: Implications for diagnosis and therapy.结直肠癌的分子特征：对诊断和治疗的启示。
Oncol Lett. 2018 Jul;16(1):9-18. doi: 10.3892/ol.2018.8679. Epub 2018 May 9.
7
Bmp signaling in colonic mesenchyme regulates stromal microenvironment and protects from polyposis initiation.Bmp 信号在结肠间质中调节基质微环境并防止息肉形成的起始。
Int J Cancer. 2016 Jun 1;138(11):2700-12. doi: 10.1002/ijc.30001. Epub 2016 Feb 10.
8
The consensus molecular subtypes of colorectal cancer.结直肠癌的共识分子亚型
Nat Med. 2015 Nov;21(11):1350-6. doi: 10.1038/nm.3967. Epub 2015 Oct 12.
9
Targeting CXCL12 from FAP-expressing carcinoma-associated fibroblasts synergizes with anti-PD-L1 immunotherapy in pancreatic cancer.针对富含纤维母细胞激活蛋白（FAP）的癌相关成纤维细胞中的 CXCL12 进行靶向治疗，与抗 PD-L1 免疫疗法联合应用于胰腺癌。
Proc Natl Acad Sci U S A. 2013 Dec 10;110(50):20212-7. doi: 10.1073/pnas.1320318110. Epub 2013 Nov 25.
10
The serrated pathway to colorectal carcinoma: current concepts and challenges.锯齿状途径与结直肠癌：当前概念与挑战。
Histopathology. 2013 Feb;62(3):367-86. doi: 10.1111/his.12055.