Hirabayashi Matthew T, Barnett Brad P
Department of Ophthalmology, University of Missouri School of Medicine, 1 Hospital Dr, Columbia, MO 65212, USA.
California LASIK & Eye, 1111 Exposition Blvd. Bldg. 200, Ste. 2000, Sacramento, CA 95815, USA.
Diagnostics (Basel). 2023 Feb 22;13(5):837. doi: 10.3390/diagnostics13050837.
The term STODS (Surgical Temporary Ocular Discomfort Syndrome) has been coined to describe the ocular surface perturbations induced by surgery. As one of the most important refractive elements of the eye, Guided Ocular Surface and Lid Disease (GOLD) optimization is fundamental to success in achieving refractive outcomes and mitigating STODS. Effective GOLD optimization and the prevention/treatment of STODS requires an understanding of the molecular, cellular, and anatomic factors that influence ocular surface microenvironment and the associated perturbations induced by surgical intervention. By reviewing the current understanding of STODS etiologies, we will attempt to outline a rationale for a tailored GOLD optimization depending on the ocular surgical insult. With a bench-to-bedside approach, we will highlight clinical examples of effective GOLD perioperative optimization that can mitigate STODS' deleterious effect on preoperative imaging and postoperative healing.
“手术性暂时性眼不适综合征”（STODS）这一术语已被创造出来，用于描述手术引起的眼表扰动。作为眼睛最重要的屈光元件之一，引导性眼表和眼睑疾病（GOLD）优化对于实现屈光手术效果和减轻STODS至关重要。有效的GOLD优化以及STODS的预防/治疗需要了解影响眼表微环境的分子、细胞和解剖学因素，以及手术干预引起的相关扰动。通过回顾目前对STODS病因的认识，我们将尝试概述根据眼部手术损伤进行定制化GOLD优化的基本原理。采用从 bench 到 bedside 的方法，我们将重点介绍有效的GOLD围手术期优化的临床实例，这些实例可以减轻STODS对术前成像和术后愈合的有害影响。
