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利用牙科全景X线片和初潮年龄进行骨质疏松症筛查。

Osteoporosis Screening Using Dental Panoramic Radiographs and Age at Menarche.

作者信息

Triantafyllopoulos George, Mitsea Anastasia, Rontogianni Aliki, Korres Demitrios

机构信息

Medical School, National and Kapodistrian University of Athens, 11527 Athens, Greece.

Dental School, National and Kapodistrian University of Athens, 11527 Athens, Greece.

出版信息

Diagnostics (Basel). 2023 Feb 24;13(5):881. doi: 10.3390/diagnostics13050881.

Abstract

Since early detection of osteoporosis is essential, the development of an efficient and cost-effective screening model would be incredibly beneficial. The aim of this study was to evaluate the diagnostic accuracy of MCW and MCI indices from dental panoramic radiographs in combination with a new variable, age at menarche, for the detection of osteoporosis. The study enrolled 150 Caucasian women (aged 45 to 86) who met the eligibility criteria, had DXA scans of the left hip and lumbar spine (L2 to L4), and were classified as osteoporotic, osteopenic, or normal based on T-score. Two observers evaluated MCW and MCI indexes on panoramic radiographs. There was a statistically significant correlation between the T-score and MCI and MCW. In addition, age at menarche had a statistically significant correlation with T-score ( = 0.006). In conclusion, in the current study, MCW proved to be more effective in detecting osteoporosis when combined with age at menarche. Individuals with MCW less than 3.0 mm and age at menarche later than 14 years old should be referred for DXA since they present high risk of osteoporosis.

摘要

由于骨质疏松症的早期检测至关重要,因此开发一种高效且具有成本效益的筛查模型将非常有益。本研究的目的是评估牙科全景X线片中的MCW和MCI指数结合初潮年龄这一新变量用于检测骨质疏松症的诊断准确性。该研究纳入了150名符合入选标准的白种女性(年龄45至86岁),她们进行了左髋部和腰椎(L2至L4)的双能X线吸收测定扫描,并根据T值被分类为骨质疏松症、骨质减少或正常。两名观察者在全景X线片上评估MCW和MCI指数。T值与MCI和MCW之间存在统计学上的显著相关性。此外,初潮年龄与T值存在统计学上的显著相关性(=0.006)。总之,在当前研究中,MCW与初潮年龄相结合时在检测骨质疏松症方面被证明更有效。MCW小于3.0毫米且初潮年龄晚于14岁的个体应转诊进行双能X线吸收测定扫描,因为他们存在骨质疏松症的高风险。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/95d4/10000716/ea95e9162bce/diagnostics-13-00881-g001.jpg

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