Dragomir Liliana, Marina Virginia, Anghele Mihaela, Anghele Aurelian-Dumitrache, Moscu Cosmina Alina
Clinical-Medical Department, Faculty of Medicine and Pharmacy, "Dunărea de Jos" University of Galati, 800201 Galati, Romania.
Medical Department of Occupational Health, Faculty of Medicine and Pharmacy, "Dunărea de Jos" University of Galati, 35 Str. Domneasca Galati, 800201 Galati, Romania.
Diagnostics (Basel). 2023 Mar 1;13(5):940. doi: 10.3390/diagnostics13050940.
MDMA (3,4-methylenedioxymethamphetamine; commonly referred to as "Molly" or "ecstasy") is a synthetic compound, structurally and pharmacologically similar to both amphetamines and mescaline. MDMA differs somewhat from traditional amphetamines in that it is not structurally similar to serotonin. Cocaine is rare and cannabis is consumed less frequently than in Western Europe. Heroin is the drug of choice for the poor in Bucharest, Romania's capital of two million people, and alcoholism is common in villages where more than a third of the population lives in poverty. By far, the most popular drugs are Legal Highs (Romanians call them "ethnobotanics"). All of these drugs have significant effects on cardiovascular function that contribute significantly to adverse events. Most adverse cardiac events occur in young adults and are potentially reversible. Poisoning among patients aged 17 years and over was commonly seen in the Emergency Departments of a large tertiary hospital in the city centre, accounting for 3.2% of all patients. In a third of the poisonings, more than one substance was used. Intoxication with ethnobotanicals was the most frequently observed, followed by use of drugs from the amphetamine group. The majority of patients presenting to the Emergency Department were male. Therefore, this study suggests further research on hazardous alcohol consumption and drug abuse.
摇头丸（3,4－亚甲基二氧甲基苯丙胺；通常称为“莫莉”或“摇头丸”）是一种合成化合物，在结构和药理上与苯丙胺类药物和三甲氧苯乙胺相似。摇头丸与传统苯丙胺类药物有所不同，因为它在结构上与血清素不相似。可卡因较为罕见，大麻的消费量也低于西欧。海洛因是罗马尼亚首都布加勒斯特（拥有两百万人口）贫困人口的首选毒品，酗酒在超过三分之一人口生活贫困的农村地区很常见。到目前为止，最受欢迎的毒品是新型毒品（罗马尼亚人称之为“民族植物药”）。所有这些毒品都会对心血管功能产生重大影响，这在很大程度上导致了不良事件的发生。大多数不良心脏事件发生在年轻人身上，并且可能是可逆的。在市中心一家大型三级医院的急诊科，17岁及以上患者的中毒情况很常见，占所有患者的3.2%。在三分之一的中毒事件中，使用了不止一种物质。民族植物药中毒是最常观察到的，其次是苯丙胺类药物的使用。到急诊科就诊的患者大多数是男性。因此，本研究建议对有害饮酒和药物滥用进行进一步研究。
