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冠状病毒与免疫反应、心肺功能康复和体力活动的关联:简要报告。

Associations between Coronavirus and Immune Response, Cardiorespiratory Fitness Rehabilitation and Physical Activity: A Brief Report.

机构信息

Department of Sports, Higher Institute of Educational Sciences of the Douro, 4500-708 Penafiel, Portugal.

CI-ISCE/ISCE Douro, 4500-708 Penafiel, Portugal.

出版信息

Int J Environ Res Public Health. 2023 Mar 6;20(5):4651. doi: 10.3390/ijerph20054651.

Abstract

COVID-19 has serious effects on cardiorespiratory capacity. In this sense, physical activity has been identified as beneficial in the treatment of cardiorespiratory diseases due to its anti-inflammatory and immunosuppressive benefits. To date, no study has been found on cardiorespiratory capacity and rehabilitation in patients cured after COVID-19. Thus, this brief report aims to relate the benefits of physical activity to cardiorespiratory function after COVID-19. It is important to know how different levels of physical activity can be related to the different symptoms of COVID-19. In view of this, the objectives of this brief report were to: (1) explore the theoretical associations between COVID-19 symptoms and physical activity; (2) compare the cardiorespiratory function of non-COVID-19 participants and post-COVID-19 patients; and (3) propose a physical activity program to improve the cardiorespiratory fitness of post-COVID-19 patients. Thus, we note that moderate-intensity physical activity (i.e., walking) has a greater beneficial effect on immune function, whereas vigorous activity (i.e., marathon running) tends to temporarily reduce immune function through an imbalance of cytokine types I and II in the hours and days after exercise. However, there is no consensus in the literature in this regard, since other investigations suggest that high-intensity training can also be beneficial, not causing clinically relevant immunosuppression. Physical activity has been shown to be beneficial in improving the clinical conditions most frequently associated with severe COVID-19. Thus, it is possible to infer that physically active individuals seem to be less exposed to the dangers of severe COVID-19 compared to non-active individuals through the benefits of physical activity in strengthening the immune system and fighting infections. The current study demonstrates that physical activity appears to be beneficial in improving the clinical conditions most often associated with severe COVID-19.

摘要

COVID-19 对心肺能力有严重影响。在这种意义上,由于其抗炎和免疫抑制作用,体力活动已被确定对心肺疾病的治疗有益。迄今为止,尚未发现关于 COVID-19 后治愈患者的心肺能力和康复的研究。因此,本简要报告旨在论述 COVID-19 后体力活动对心肺功能的益处。了解不同水平的体力活动如何与 COVID-19 的不同症状相关非常重要。有鉴于此,本简要报告的目的是:(1)探讨 COVID-19 症状与体力活动之间的理论关联;(2)比较非 COVID-19 参与者和 COVID-19 后患者的心肺功能;(3)提出一项体力活动计划,以提高 COVID-19 后患者的心肺健康水平。因此,我们注意到,中等强度的体力活动(例如,散步)对免疫功能具有更大的有益影响,而剧烈活动(例如,马拉松跑步)则倾向于通过在运动后数小时和数天内 I 型和 II 型细胞因子类型的不平衡暂时降低免疫功能。但是,在这方面,文献中尚无共识,因为其他研究表明,高强度训练也可能有益,不会引起临床上相关的免疫抑制。体力活动已被证明有益于改善与严重 COVID-19 最常相关的临床状况。因此,可以推断,与非活跃个体相比,活跃个体似乎通过体力活动增强免疫系统和抵抗感染的益处,较少暴露于严重 COVID-19 的危险之下。本研究表明,体力活动似乎有益于改善与严重 COVID-19 最常相关的临床状况。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b445/10001454/ff7f794a9cce/ijerph-20-04651-g001.jpg

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