Zhengzhou Research Base, State Key Laboratory of Cotton Biology, School of Agricultural Sciences, Zhengzhou University, Zhengzhou 450001, China.
State Key Laboratory of Cotton Biology, Institute of Cotton Research, Chinese Academy of Agricultural Sciences, Anyang 455000, China.
Int J Mol Sci. 2023 Feb 23;24(5):4392. doi: 10.3390/ijms24054392.
Regeneration refers to the process by which organisms repair and replace lost tissues and organs. Regeneration is widespread in plants and animals; however, the regeneration capabilities of different species vary greatly. Stem cells form the basis for animal and plant regeneration. The essential developmental processes of animals and plants involve totipotent stem cells (fertilized eggs), which develop into pluripotent stem cells and unipotent stem cells. Stem cells and their metabolites are widely used in agriculture, animal husbandry, environmental protection, and regenerative medicine. In this review, we discuss the similarities and differences in animal and plant tissue regeneration, as well as the signaling pathways and key genes involved in the regulation of regeneration, to provide ideas for practical applications in agriculture and human organ regeneration and to expand the application of regeneration technology in the future.
再生是指生物修复和替换失去的组织和器官的过程。再生在植物和动物中广泛存在;然而,不同物种的再生能力有很大的差异。干细胞是动物和植物再生的基础。动物和植物的基本发育过程涉及全能干细胞(受精卵),它们发育成多能干细胞和单能干细胞。干细胞及其代谢物广泛应用于农业、畜牧业、环境保护和再生医学。在这篇综述中,我们讨论了动物和植物组织再生的异同,以及调节再生的信号通路和关键基因,为农业和人类器官再生的实际应用提供思路,并扩展再生技术在未来的应用。