Department of Clinical and Experimental Medicine, University of Pisa, Via Roma 67, 56126 Pisa, Italy.
Nutrients. 2023 Mar 2;15(5):1256. doi: 10.3390/nu15051256.
A number of studies in the general population showed that healthy dietary patterns, such as the Mediterranean Diet, can improve or prevent the development of several chronic diseases and are associated with a significant reduction in all-cause and cardiovascular mortality. The Mediterranean diet may also have favorable effects for the prevention of chronic kidney disease (CKD), but no evidence of renoprotection exists in CKD patients. The Mediterranean Renal (MedRen) diet is an adaptation of the Mediterranean diet recommendations comprising a quantitative reduction in the RDA values of protein, salt and phosphate intake for the general population. Hence, MedRen supplies 0.8 g/Kg of protein, 6 g of salt and less than 800 mg of phosphate daily. Obviously, there is a preference for products of plant origin, which contain more alkali, fibers, unsaturated fatty acids than animal-based food. The MedRen diet can be implemented easily in mild-to-moderate stages of CKD with good results, both in terms of adherence to prescriptions and metabolic compensation. In our opinion, it should be the first step of CKD stage 3 nutritional management. This paper describes the features and reports our experience in the implementation of the MedRen diet as an early nutritional approach to CKD.
一些针对普通人群的研究表明,健康的饮食模式,如地中海饮食,可以改善或预防多种慢性疾病的发生,并与全因和心血管死亡率的显著降低相关。地中海饮食对预防慢性肾脏病(CKD)可能也有有利影响,但在 CKD 患者中没有肾脏保护作用的证据。地中海肾脏饮食(MedRen)是地中海饮食建议的一种适应,包括对普通人群蛋白质、盐和磷酸盐摄入量的 RDA 值进行定量减少。因此,MedRen 每天供应 0.8 克/公斤蛋白质、6 克盐和少于 800 毫克的磷酸盐。显然,人们更喜欢植物性产品,这些产品含有比动物性食物更多的碱、纤维和不饱和脂肪酸。MedRen 饮食在 CKD 的轻度至中度阶段很容易实施,并且在遵守医嘱和代谢补偿方面都有很好的效果。在我们看来,它应该是 CKD 第 3 阶段营养管理的第一步。本文介绍了 MedRen 饮食的特点,并报告了我们在实施 MedRen 饮食作为 CKD 早期营养治疗方面的经验。