Kurmaev D P, Bulgakova S V, Treneva E V, Chetverikova I S, Bashinskaya S A
Samara State Medical University, 89 Chapaevskaya str., Samara 443099, Russian Federation, e-mail:
Adv Gerontol. 2022;35(6):818-826.
One of the leading geriatric syndromes, which has been included in the International Classification of Diseases ICD-10 since 2016, is sarcopenia. Sarcopenia is a progressive gener-alized disease accompanied by a loss of strength, mass, and skeletal muscle function. This dis-ease can lead to a decrease in working capacity, impaired ability to self-service, disability, and an increased risk of premature death. Type 2 diabetes mellitus (T2DM) plays an important role among the chronic non-infectious pathology of elderly and senile patients. T2DM is a serious health burden for older people, affecting approximately 25% of people over 65 years of age. This percentage is expected to rise sharply in the coming decades due to the increase in the life expectancy of the population observed in recent years. In addition to microvascular and macro-vascular complications, sarcopenia has been described as a new complication of diabetes melli-tus in the elderly. T2DM increases the risk of developing sarcopenia threefold. It is of interest to consider the mechanisms of the relationship between sarcopenia and type 2 diabetes mellitus in geriatric patients.
自2016年起被纳入《国际疾病分类》ICD - 10的主要老年综合征之一是肌肉减少症。肌肉减少症是一种进行性全身性疾病，伴有力量、质量和骨骼肌功能丧失。这种疾病会导致工作能力下降、自我服务能力受损、残疾以及过早死亡风险增加。2型糖尿病（T2DM）在老年和高龄患者的慢性非传染性疾病中起着重要作用。T2DM对老年人来说是一项严重的健康负担，影响着约25%的65岁以上人群。由于近年来观察到的人口预期寿命增加，预计这一比例在未来几十年将急剧上升。除了微血管和大血管并发症外，肌肉减少症已被描述为老年糖尿病患者的一种新并发症。T2DM使发生肌肉减少症的风险增加两倍。研究老年患者中肌肉减少症与2型糖尿病之间的关系机制很有意义。
