Jeyaraman Madhan, Jain Vijay Kumar, Vaishya Raju
Department of Orthopaedics, ACS Medical College and Hospital, Dr MGR Educational and Research Institute, Chennai, 600056, Tamil Nadu, India.
Department of Orthopaedics, Atal Bihari Vajpayee Institute of Medical Sciences, Dr Ram Manohar Lohia Hospital, New Delhi, 110001, India.
J Clin Orthop Trauma. 2023 Feb 25;39:102145. doi: 10.1016/j.jcot.2023.102145. eCollection 2023 Apr.
Globally, 25% of the population is infected with tuberculosis, which poses a leading cause of death worldwide. The transmission of tuberculosis (TB) during organ transplant is reported in the literature whereas only one report has been published on the transmission of TB, during bone allograft transplantation. In the US, in May 2021, an outbreak of TB occurred in patients undergoing spine surgery with bone allograft. This bone graft was retrieved from 80 years deceased donor with latent TB, which was not diagnosed earlier. The recipients were started with a long course of anti-tuberculous drugs. This review narrates the pathway of TB spread among transplant recipients and the strategies to be followed while performing organ or tissue transplantation.
全球范围内，25%的人口感染了结核病，这是全球主要的死亡原因。文献报道了器官移植期间结核病（TB）的传播情况，而关于骨移植过程中结核病传播的报告仅有一篇。在美国，2021年5月，接受脊柱手术并使用骨移植的患者中爆发了结核病。该骨移植取自一名80岁的已故捐赠者，其患有潜伏性结核病，但此前未被诊断出来。接受者开始了长期的抗结核药物治疗。这篇综述阐述了结核病在移植受者中的传播途径以及进行器官或组织移植时应遵循的策略。
