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口腔健康相关生活质量以及活动期和恢复期 COVID-19 患者味觉丧失和口干的患病率。

Oral health related quality of life and the prevalence of ageusia and xerostomia in active and recovered COVID-19 Patients.

机构信息

Prosthodontics Department, Altamash Institute of Dental Medicine, Karachi, Pakistan.

Prosthodontics Department, University Sains Malaysia, Kelantan, Malaysia.

出版信息

PeerJ. 2023 Mar 6;11:e14860. doi: 10.7717/peerj.14860. eCollection 2023.

Abstract

BACKGROUND

Salivary disturbance is associated with patients who either have an active coronavirus disease 2019 (COVID-19) or have recovered from coronavirus infection along with loss of taste sensation. In addition, COVID-19 infection can drastically compromise quality of life of individuals.

OBJECTIVE

This study aimed to analyze xerostomia, ageusia and the oral health impact in coronavirus disease-19 patients utilizing the Xerostomia Inventory scale-(XI) and the Oral Health Impact Profile-14.

METHODS

In this cross-sectional survey-based study, data was collected from 301 patients who suffered and recovered from COVID-19. Using Google Forms, a questionnaire was developed and circulated amongst those who were infected and recovered from coronavirus infection. The Xerostomia Inventory (XI) and Oral Health Impact Profile-14 were used to assess the degree and quality of life. A paired T-test and Chi-square test were used to analyze the effect on xerostomia inventory scale-(XI) and OHIP-14 scale scores. A -value of 0.05 was considered as statistically significant.

RESULTS

Among 301 participants, 54.8% were females. The prevalence of xerostomia in participants with active COVID-19 disease was 39.53% and after recovery 34.88%. The total OHIP-14 scores for patients in the active phase of infection was 12.09, while 12.68 in recovered patients. A significant difference was found between the mean scores of the xerostomia inventory scale-11 and OHIP-14 in active and recovered COVID patients.

CONCLUSION

A higher prevalence of xerostomia was found in COVID-19 infected patients (39.53%) compared to recovered patients (34.88%). In addition, more than 70% reported aguesia. COVID-19 had a significantly higher compromising impact on oral function of active infected patients compared to recovered patients.

摘要

背景

唾液紊乱与患有活动性 2019 年冠状病毒病(COVID-19)或从冠状病毒感染中康复的患者有关,同时伴有味觉丧失。此外,COVID-19 感染会极大地降低个体的生活质量。

目的

本研究旨在利用口干症量表(XI)和口腔健康影响概况-14 分析 COVID-19 患者的口干症、味觉丧失和口腔健康影响。

方法

在这项基于横断面调查的研究中,从 301 名患有和已从 COVID-19 中康复的患者中收集数据。使用 Google 表单,开发了一个问卷并分发给那些感染和从冠状病毒感染中康复的人。使用口干量表(XI)和口腔健康影响概况-14 评估程度和生活质量。使用配对 t 检验和卡方检验分析口干量表(XI)和 OHIP-14 量表评分的影响。a 值为 0.05 被认为具有统计学意义。

结果

在 301 名参与者中,54.8%为女性。在患有活动性 COVID-19 疾病的参与者中,口干的患病率为 39.53%,而在康复后为 34.88%。感染活跃期患者的总 OHIP-14 评分为 12.09,而康复患者为 12.68。在活跃期和恢复期 COVID 患者的口干量表 11 和 OHIP-14 的平均评分之间发现了显著差异。

结论

与康复患者(34.88%)相比,COVID-19 感染患者(39.53%)口干症的患病率更高。此外,超过 70%的患者报告味觉丧失。与康复患者相比,COVID-19 对活跃感染患者的口腔功能有显著更高的影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/236d/9997189/c36a6b9b016f/peerj-11-14860-g001.jpg

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