Monti Sara, Schäfer Valentin Sebastian, Muratore Francesco, Salvarani Carlo, Montecucco Carlomaurizio, Luqmani Raashid
Department of Internal Medicine and Therapeutics, Università di Pavia, Pavia, Italy.
Division of Rheumatology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
Front Med (Lausanne). 2023 Feb 23;10:1125141. doi: 10.3389/fmed.2023.1125141. eCollection 2023.
This mini-review offers a critical appraisal of the currently employed imaging or histopathological tools to diagnose and monitor giant cell arteritis (GCA). An overview of the most updated evidence and current application of color duplex ultrasonography (US), temporal artery biopsy (TAB), 18-fluorodeoxyglucose [18F] FDG-PET/CT, magnetic resonance imaging, and computed tomography angiography is provided. The main limitations of each tool, and the most relevant research developments are discussed. The review highlights the complementary value of the available modalities to ensure a correct diagnosis of GCA, and to provide valuable prognostic information. Novel evidence is accumulating to support the role of imaging, and particularly US, as a monitoring tool for the disease, opening new perspectives for the future management of large vessel vasculitis.
本综述对目前用于诊断和监测巨细胞动脉炎(GCA)的影像学或组织病理学工具进行了批判性评估。提供了彩色双功超声(US)、颞动脉活检(TAB)、18氟脱氧葡萄糖[18F]FDG-PET/CT、磁共振成像和计算机断层血管造影的最新证据及当前应用概述。讨论了每种工具的主要局限性以及最相关的研究进展。该综述强调了现有检查方法的互补价值,以确保正确诊断GCA,并提供有价值的预后信息。越来越多的新证据支持影像学尤其是US作为该疾病监测工具的作用,为大血管血管炎的未来管理开辟了新的前景。