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估算主动检测和隔离对骨髓移植病房感染的影响。

Estimating the effect of active detection and isolation on infections in a bone marrow transplant unit.

机构信息

Department of Mathematics and Applied Mathematics, Virginia Commonwealth University, Richmond, Virginia.

Division of Infectious Diseases, Virginia Commonwealth University, Richmond, Virginia.

出版信息

Infect Control Hosp Epidemiol. 2023 Oct;44(10):1614-1619. doi: 10.1017/ice.2023.37. Epub 2023 Mar 13.

DOI:10.1017/ice.2023.37
PMID:36912338
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10587385/
Abstract

OBJECTIVE

To model the effects of active detection and isolation (ADI) regarding infection (CDI) in the bone marrow transplant (BMT) unit of our hospital.

SETTING

ADI was implemented in a 21-patient bone marrow unit.

PATIENTS

Patients were bone marrow recipients on this unit.

INTERVENTIONS

We compared active ADI, in which patients who tested positive for colonization of before their hospital stay were placed under extra contact precautions, with cases not under ADI.

RESULTS

Within the BMT unit, ADI reduced total cases of CDI by 24.5% per year and reduced hospital-acquired cases by ∼84%. The results from our simulations also suggest that ADI can save ∼$67,600 per year in healthcare costs.

CONCLUSIONS

Institutions with active BMT units should consider implementing ADI.

摘要

目的

对我院骨髓移植（BMT）病房主动检测和隔离（ADI）对感染（CDI）的影响进行建模。

地点

ADI 在一个 21 名患者的骨髓病房实施。

患者

该病房的骨髓移植受者。

干预措施

我们比较了主动 ADI，即在患者住院前检测出定植阳性的患者采取额外的接触预防措施，与未进行 ADI 的病例。

结果

在 BMT 病房，ADI 使每年 CDI 总病例减少 24.5%，并减少了约 84%的医院获得性病例。我们的模拟结果还表明，ADI 每年可节省约 67600 美元的医疗保健费用。

结论

有积极的 BMT 病房的机构应考虑实施 ADI。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6c8e/10587385/3fd342753740/S0899823X23000375_fig5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6c8e/10587385/683b4260479d/S0899823X23000375_fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6c8e/10587385/d2fe4b36b40e/S0899823X23000375_fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6c8e/10587385/9c0025181a64/S0899823X23000375_fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6c8e/10587385/9387fb38c33e/S0899823X23000375_fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6c8e/10587385/3fd342753740/S0899823X23000375_fig5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6c8e/10587385/683b4260479d/S0899823X23000375_fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6c8e/10587385/d2fe4b36b40e/S0899823X23000375_fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6c8e/10587385/9c0025181a64/S0899823X23000375_fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6c8e/10587385/9387fb38c33e/S0899823X23000375_fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6c8e/10587385/3fd342753740/S0899823X23000375_fig5.jpg

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