Department of Anesthesiology and Intensive Care Medicine, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki, Nagasaki, 852-8501, Japan.
Department of Anesthesia, National Hospital Organization Shizuoka Medical Center, Shizuoka, Japan.
J Anesth. 2023 Jun;37(3):340-356. doi: 10.1007/s00540-023-03177-5. Epub 2023 Mar 13.
This practical guide has been developed to ensure safe and effective sedation performed in adult patients outside of the operating room, for instance in intensive care units and dental treatment rooms and in the field of palliative care. Sedation levels are classified based on level of consciousness, airway reflex, spontaneous ventilation, and cardiovascular function. Deep sedation induces loss of consciousness and protective reflexes, and can cause respiratory depression and pulmonary aspiration. Invasive medical procedures necessitating deep sedation include cardiac ablation, endoscopic submucosal dissection, and internal radiation therapy. Appropriate analgesia is necessary for procedures that require deep sedation. The sedationist should evaluate the risks of the planned procedure, explain the sedation process to the patient, and obtain the patient's informed consent. Major parameters to be evaluated preoperatively are the patient's airway and general condition. Equipment, instruments, and drugs necessary for emergency situations should be defined and routinely maintained. To prevent aspiration, patients scheduled for moderate or deep sedation should fast preoperatively. In both inpatients and outpatients, biological monitoring should be continued until the discharge criteria are met. Anesthesiologists should be involved in management systems that ensure safe and effective sedation even if they do not personally perform all sedation procedures.
本实用指南旨在确保在手术室外为成人患者进行安全有效的镇静,例如在重症监护病房和牙科治疗室以及姑息治疗领域。镇静水平根据意识水平、气道反射、自主通气和心血管功能进行分类。深度镇静会导致意识丧失和保护反射丧失,并可能导致呼吸抑制和肺吸入。需要深度镇静的有创医疗程序包括心脏消融、内镜黏膜下剥离和内部放射治疗。需要深度镇静的程序应给予适当的镇痛。镇静医师应评估计划程序的风险,向患者解释镇静过程,并获得患者的知情同意。术前需要评估的主要参数是患者的气道和一般情况。应定义并定期维护用于紧急情况的设备、仪器和药物。为了防止吸入,计划接受中度或深度镇静的患者应在术前禁食。在住院患者和门诊患者中,应持续进行生物监测,直到达到出院标准。即使麻醉师本人不执行所有镇静程序,也应参与管理系统,以确保安全有效的镇静。