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COVID-19 pandemic is associated with mechanical complications in patients with ST-elevation myocardial infarction.COVID-19 大流行与 ST 段抬高型心肌梗死患者的机械并发症有关。
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从 COVID-19 对 ST 段抬高型心肌梗死患者治疗时间和临床结局的影响中恢复:一项中期分析。

Recovery From the Impact of COVID-19 on Treatment Times and Clinical Outcomes of Patients With ST-Segment Elevation Myocardial Infarction: An Interim Analysis.

机构信息

Division of Hospital Medicine, Hartford Hospital, Hartford, Connecticut.

Division of Cardiology, Hartford Hospital, Hartford, Connecticut.

出版信息

Tex Heart Inst J. 2023 Mar 1;50(2). doi: 10.14503/THIJ-22-7919.

DOI:10.14503/THIJ-22-7919
PMID:36913275
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10178640/
Abstract

BACKGROUND

Previous studies have documented a negative impact of the COVID-19 pandemic on emergent percutaneous treatment of patients with ST-segment elevation myocardial infarction (STEMI), but few have examined recovery of healthcare systems in restoring prepandemic STEMI care.

METHODS

Retrospective analysis was performed of data from 789 patients with STEMI from a large tertiary medical center treated with percutaneous coronary intervention between January 1, 2019, and December 31, 2021.

RESULTS

For patients with STEMI presenting to the emergency department, median time from door to balloon was 37 minutes in 2019, 53 minutes in 2020, and 48 minutes in 2021 (P < .001), whereas median time from first medical contact to device changed from 70 to 82 to 75 minutes, respectively (P = .002). Treatment time changes in 2020 and 2021 correlated with median emergency department evaluation time (30 to 41 to 22 minutes, respectively; P = .001) but not median catheterization laboratory revascularization time. For transfer patients, median time from first medical contact to device changed from 110 to 133 to 118 minutes, respectively (P = .005). In 2020 and 2021, patients with STEMI had greater late presentation (P = .028) and late mechanical complications (P = .021), with nonsignificant increases in yearly in-hospital mortality (3.6% to 5.2% to 6.4%; P = .352).

CONCLUSION

COVID-19 was associated with worsening STEMI treatment times and outcomes in 2020. Despite improving treatment times in 2021, in-hospital mortality had not decreased in the setting of a persistent increase in late patient presentation and associated STEMI complications.

摘要

背景

先前的研究记录了 COVID-19 大流行对 ST 段抬高型心肌梗死(STEMI)患者紧急经皮治疗的负面影响,但很少有研究检查医疗系统在恢复大流行前 STEMI 治疗方面的恢复情况。

方法

对一家大型三级医疗中心 2019 年 1 月 1 日至 2021 年 12 月 31 日期间接受经皮冠状动脉介入治疗的 789 例 STEMI 患者的数据进行回顾性分析。

结果

对于急诊科就诊的 STEMI 患者,从门到球囊的中位数时间在 2019 年为 37 分钟,2020 年为 53 分钟,2021 年为 48 分钟(P <.001),而从首次医疗接触到器械的中位数时间分别从 70 分钟变为 82 分钟再变为 75 分钟(P =.002)。2020 年和 2021 年的治疗时间变化与中位数急诊科评估时间相关(分别为 30 分钟至 41 分钟至 22 分钟;P =.001),但与中位数导管室血运重建时间无关。对于转院患者,从首次医疗接触到器械的中位数时间分别从 110 分钟变为 133 分钟再变为 118 分钟(P =.005)。2020 年和 2021 年,STEMI 患者的晚期表现(P =.028)和晚期机械并发症(P =.021)增加,每年院内死亡率无显著增加(分别为 3.6%、5.2%和 6.4%;P =.352)。

结论

COVID-19 与 2020 年 STEMI 治疗时间和结局恶化有关。尽管 2021 年治疗时间有所改善,但在晚期患者就诊和相关 STEMI 并发症持续增加的情况下,院内死亡率并未降低。