• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

在门诊环境下,应用 CO2 点阵激光治疗慢性增生性烧伤瘢痕具有良好的耐受性。

Treatment of Chronic Hypertrophic Burn Scars With a Fractional CO 2 Laser Is Well Tolerated in an Outpatient Clinic Setting.

机构信息

From the Skin and Laser Center.

Division of Trauma, Acute Care Surgery, and Burns.

出版信息

Ann Plast Surg. 2023 May 1;90(5):444-446. doi: 10.1097/SAP.0000000000003526. Epub 2023 Mar 8.

DOI:10.1097/SAP.0000000000003526
PMID:36913562
Abstract

INTRODUCTION

The necessity of treating hypertrophic burn scars has expanded significantly with increased burn survivorship. Ablative lasers, such as carbon dioxide (CO 2 ) lasers, have been the most common nonoperative option for improving functional outcomes in severe recalcitrant hypertrophic burn scars. However, the overwhelming majority of ablative lasers used for this indication require a combination of systemic analgesia, sedation, and/or general anesthesia due to the painful nature of the procedure. More recently, the technology of ablative lasers has advanced and is more tolerable than their first-generation counterparts. Herein, we hypothesized that refractory hypertrophic burn scars can be treated by a CO 2 laser in an outpatient clinic.

METHODS

We enrolled 17 consecutive patients with chronic hypertrophic burn scars that were treated with a CO 2 laser. All patients were treated in the outpatient clinic with a combination of a topical solution (23% lidocaine and 7% tetracaine) applied to the scar 30 minutes before the procedure, Cryo 6 air chiller by Zimmer, and some patients received a mixture of N 2 O/O 2 . Laser treatments were repeated every 4 to 8 weeks until the patient's goals were met. Each patient completed a standardized questionnaire to assess tolerability and patient satisfaction of functional results.

RESULTS

All patients tolerated the laser well in the outpatient clinic setting, with 0% indicating "not tolerable," 70.6% "tolerable," and 29.4% "very tolerable." Each patient received more than 1 laser treatment for the following complaints: decreased range of motion (n = 16, 94.1%), pain (n = 11, 64.7%), or pruritis (n = 12, 70.6%). Patients were also satisfied with the results of the laser treatments ("no improvement or worsened" = 0%, "improved" = 47.1%, and "significant improvement" = 52.9%). The age of patient, type of burn, location of burn, presence of skin graft, or age of scar did not significantly affect the tolerability of treatment or satisfaction of outcome.

CONCLUSIONS

The treatment of chronic hypertrophic burn scars with a CO 2 laser is well tolerated in an outpatient clinic setting in select patients. Patients reported a high level of satisfaction with notable improvement in functional and cosmetic outcomes.

摘要

引言

随着烧伤存活率的提高,治疗增生性烧伤瘢痕的必要性显著增加。二氧化碳(CO 2 )激光等烧蚀性激光已成为改善严重难治性增生性烧伤瘢痕功能结局的最常用非手术选择。然而,由于该治疗过程具有疼痛性质,绝大多数用于该适应症的烧蚀性激光需要联合全身镇痛、镇静和/或全身麻醉。最近,烧蚀性激光技术已经发展,比第一代产品更具耐受性。在此,我们假设可以在门诊诊所通过 CO 2 激光治疗难治性增生性烧伤瘢痕。

方法

我们纳入了 17 例慢性增生性烧伤瘢痕患者,他们接受了 CO 2 激光治疗。所有患者均在门诊接受治疗,在治疗前 30 分钟在瘢痕上涂抹一种包含 23%利多卡因和 7%丁卡因的溶液,使用 Zimmer 生产的 Cryo 6 空气冷却器,部分患者接受 N 2 O/O 2 混合物。激光治疗每 4 至 8 周重复一次,直到患者达到治疗目标。每位患者完成一份标准化问卷,以评估对功能结果的耐受性和患者满意度。

结果

所有患者均能在门诊环境中耐受激光治疗,0%表示“不能耐受”,70.6%表示“可耐受”,29.4%表示“非常耐受”。每位患者接受了多次激光治疗,以下为主要治疗诉求:活动度受限(n = 16,94.1%)、疼痛(n = 11,64.7%)或瘙痒(n = 12,70.6%)。患者对激光治疗的效果也非常满意(“无改善或恶化”= 0%,“改善”= 47.1%,“显著改善”= 52.9%)。患者的年龄、烧伤类型、烧伤位置、是否存在皮瓣或瘢痕年龄均不会显著影响治疗的耐受性或结果的满意度。

结论

在选择的患者中,CO 2 激光治疗慢性增生性烧伤瘢痕在门诊环境中耐受性良好。患者报告对功能和美容结果有显著改善,满意度较高。

相似文献

1
Treatment of Chronic Hypertrophic Burn Scars With a Fractional CO 2 Laser Is Well Tolerated in an Outpatient Clinic Setting.在门诊环境下,应用 CO2 点阵激光治疗慢性增生性烧伤瘢痕具有良好的耐受性。
Ann Plast Surg. 2023 May 1;90(5):444-446. doi: 10.1097/SAP.0000000000003526. Epub 2023 Mar 8.
2
[Clinical effects of sequential laser treatments on early stage hypertrophic burn scars].序贯激光治疗对早期增生性烧伤瘢痕的临床疗效
Zhonghua Shao Shang Za Zhi. 2018 Sep 20;34(9):615-623. doi: 10.3760/cma.j.issn.1009-2587.2018.09.011.
3
Ultrapulsed fractional ablative carbon dioxide laser treatment of hypertrophic burn scars: evaluation of an in-patient controlled, standardized treatment approach.超脉冲分次剥脱性二氧化碳激光治疗肥厚性烧伤瘢痕:一项住院患者对照、标准化治疗方法的评估
Lasers Med Sci. 2017 Jul;32(5):1031-1040. doi: 10.1007/s10103-017-2204-z. Epub 2017 Apr 12.
4
Combination treatment utilizing fractional ablative and continuous wave CO lasers for hypertrophic burn scars.利用分段式消融和连续波 CO 激光联合治疗增生性烧伤瘢痕。
Burns. 2021 Aug;47(5):1084-1093. doi: 10.1016/j.burns.2020.10.015. Epub 2020 Nov 7.
5
Fractional CO2 Laser Treatment Outcomes for Pediatric Hypertrophic Burn Scars.小儿增生性烧伤瘢痕的二氧化碳点阵激光治疗效果
J Burn Care Res. 2019 Jun 21;40(4):386-391. doi: 10.1093/jbcr/irz046.
6
Hypertrophic Scar Improvement by Early Intervention With Ablative Fractional Carbon Dioxide Laser Treatment.早期采用消融性二氧化碳点阵激光治疗改善增生性瘢痕。
Lasers Surg Med. 2021 Apr;53(4):450-457. doi: 10.1002/lsm.23301. Epub 2020 Jul 16.
7
Laser Treatment of Burn Scars.烧伤瘢痕的激光治疗
Actas Dermosifiliogr. 2022 Nov-Dec;113(10):938-944. doi: 10.1016/j.ad.2022.06.018. Epub 2022 Aug 11.
8
Treatment of burn hypertrophic scar with fractional ablative laser-assisted drug delivery can decrease levels of hyperpigmentation.分幅消融激光辅助药物递送治疗烧伤增生性瘢痕可降低色素沉着水平。
Lasers Surg Med. 2023 Jul;55(5):471-479. doi: 10.1002/lsm.23662. Epub 2023 Apr 13.
9
Fractional Ablative Laser Therapy is an Effective Treatment for Hypertrophic Burn Scars: A Prospective Study of Objective and Subjective Outcomes.分粹性激光消融术治疗增生性烧伤瘢痕的有效性:一项客观和主观结局的前瞻性研究。
Ann Surg. 2021 Dec 1;274(6):e574-e580. doi: 10.1097/SLA.0000000000003576.
10
Fractional CO2 laser therapy of hypertrophic scars - evaluation of efficacy and treatment protocol optimization.增生性瘢痕的 CO2 激光分次治疗-疗效评估和治疗方案优化。
Acta Chir Plast. 2021 Winter;63(4):171-180. doi: 10.48095/ccachp2021171.

引用本文的文献

1
The Pathophysiology and Management of Pathologic Scarring-a Contemporary Review.病理性瘢痕的病理生理学与管理——当代综述
Adv Wound Care (New Rochelle). 2025 Jan;14(1):48-64. doi: 10.1089/wound.2023.0185. Epub 2024 Apr 25.