Gross Evan G, Laskay Nicholas M B, Mooney James, McLeod M Chandler, Atchley Travis J, Estevez-Ordonez Dagoberto, Godzik Jakub
Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Department of Neurological Surgery, University of Alabama at Birmingham, Birmingham, Alabama, USA.
World Neurosurg. 2023 May;173:e830-e837. doi: 10.1016/j.wneu.2023.03.034. Epub 2023 Mar 11.
As the obesity epidemic grows, the number of morbidly obese patients undergoing anterior cervical discectomy and fusion (ACDF) continues to increase. Despite the association of obesity with perioperative complications in anterior cervical surgery, the impact of morbid obesity on ACDF complications remains controversial, and studies examining morbidly obese cohorts are limited.
A single-institution, retrospective analysis of patients undergoing ACDF from September 2010 to February 2022 was performed. Demographic, intraoperative, and postoperative data were collected via review of the electronic medical record. Patients were categorized as nonobese (body mass index [BMI] <30), obese (BMI 30-39.9), or morbidly obese (BMI ≥40). Associations of BMI class with discharge disposition, length of surgery, and length of stay were assessed using multivariable logistic regression, multivariable linear regression, and negative binomial regression, respectively.
The study included 670 patients undergoing single-level or multilevel ACDF: 413 (61.6%) nonobese, 226 (33.7%) obese, and 31 (4.6%) morbidly obese patients. BMI class was associated with prior history of deep venous thrombosis (P < 0.01), pulmonary thromboembolism (P < 0.05), and diabetes mellitus (P < 0.001). In bivariate analysis, there was no significant association between BMI class and reoperation or readmission rates at 30, 60, or 365 days postoperatively. In multivariable analysis, greater BMI class was associated with increased length of surgery (P = 0.03), but not length of stay or discharge disposition.
For patients undergoing ACDF, greater BMI class was associated with increased length of surgery, but not reoperation rate, readmission rate, length of stay, or discharge disposition.
随着肥胖症的流行,接受颈椎前路椎间盘切除融合术(ACDF)的病态肥胖患者数量持续增加。尽管肥胖与颈椎前路手术的围手术期并发症有关,但病态肥胖对ACDF并发症的影响仍存在争议,且针对病态肥胖队列的研究有限。
对2010年9月至2022年2月期间接受ACDF的患者进行单机构回顾性分析。通过查阅电子病历收集人口统计学、术中及术后数据。患者分为非肥胖(体重指数[BMI]<30)、肥胖(BMI 30-39.9)或病态肥胖(BMI≥40)。分别采用多变量逻辑回归、多变量线性回归和负二项回归评估BMI类别与出院处置、手术时长和住院时长之间的关联。
该研究纳入了670例行单节段或多节段ACDF的患者:413例(61.6%)非肥胖患者、226例(33.7%)肥胖患者和31例(4.6%)病态肥胖患者。BMI类别与深静脉血栓形成既往史(P<0.01)、肺血栓栓塞(P<0.05)和糖尿病(P<0.001)相关。在双变量分析中,BMI类别与术后30、60或365天的再次手术或再入院率之间无显著关联。在多变量分析中,较高的BMI类别与手术时长增加相关(P=0.03),但与住院时长或出院处置无关。
对于接受ACDF的患者,较高的BMI类别与手术时长增加相关,但与再次手术率、再入院率、住院时长或出院处置无关。