Department of Urology, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Nat Rev Urol. 2023 Jun;20(6):330-331. doi: 10.1038/s41585-023-00749-8.
The cellular action of SARS-CoV-2, the virus responsible for the COVID-19 global pandemic, is dependent on a specific combination of receptors and cofactors. These proteins are now known to be expressed in normal kidney tubule tissue and renal cell carcinoma cells, representing possible targets for budding therapeutic modalities.
SARS-CoV-2 病毒是导致 COVID-19 全球大流行的罪魁祸首,其细胞作用依赖于特定的受体和辅助因子组合。这些蛋白现已被证实存在于正常的肾小管组织和肾细胞癌细胞中,这代表了新型治疗方法的可能靶点。