Lam Kayla, Selim Mohammad
Internal Medicine, Creighton University School of Medicine, Omaha, USA.
Cureus. 2023 Feb 9;15(2):e34810. doi: 10.7759/cureus.34810. eCollection 2023 Feb.
Antiphospholipid syndrome (APS) is a condition in which the body produces antiphospholipid antibodies, resulting in arterial and venous thrombosis. Catastrophic antiphospholipid syndrome (CAPS) is a rare APS subtype characterized by acute thrombotic microangiography. Antiphospholipid antibodies cause thrombosis through activating and inhibiting properties. CAPS is caused by conditions or factors that trigger the production of antiphospholipid antibodies: genetics that increases the risk of antiphospholipid antibody-associated thrombosis, infection, surgery, medications, and malignancy. We present a unique case of CAPS in a 63-year-old male patient.
抗磷脂综合征(APS)是一种身体产生抗磷脂抗体,从而导致动脉和静脉血栓形成的病症。灾难性抗磷脂综合征(CAPS)是一种罕见的APS亚型,其特征为急性血栓性微血管病。抗磷脂抗体通过激活和抑制特性导致血栓形成。CAPS由触发抗磷脂抗体产生的状况或因素引起:增加抗磷脂抗体相关血栓形成风险的遗传学因素、感染、手术、药物和恶性肿瘤。我们报告了一例63岁男性患者的独特CAPS病例。